You are viewing an incomplete version of our website. Please click to reload the website as full version.

Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody

Details for Product No. ABIN108591, Supplier: Log in to see
Antigen
  • AL022939
  • bZ1G18.4
  • C1
  • C2
  • D14Wsu171e
  • fb57h12
  • fi16b11
  • HNRNP
  • hnrnp-C
  • HNRNPC
  • hnRNP C
  • hnRNPC1
  • hnRNPC2
  • Hnrpc
  • HNRPC
  • Hnrpc1
  • Hnrpc2
  • MGC53243
  • SNRPC
  • wu:fb57h12
  • wu:fi16b11
  • zgc:55701
Reactivity
Chicken, Hamster, Human, Monkey
83
43
38
9
4
4
4
3
2
2
1
1
Host
Mouse
76
7
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
69
39
31
26
21
11
11
8
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen RNPs eluted from oligo (dT) cellulose column
Clone 4F4
Isotype IgG1
Specificity This antibody recognizes the two hnRNP C proteins of 41 and 43 kDa in human cells, and the corresponding proteins in monkey hamster chicken.
Purification Protein A
Alternative Name hnRNP C1+C2 (HNRNPC Antibody Abstract)
Background Synonyms:
C1 antibody,C2 antibody,Heterogeneous nuclear ribonucleoprotein C antibody,Heterogeneous nuclearribonucleoproteins C1/C2 antibody,HNRNP antibody,hnRNP C1 / hnRNP C2 antibody,hnRNP C1/C2 antibody,hnRNPCantibody,HNRPC antibody,HNRPC_HUMAN antibody,MGC104306 antibody,MGC105117 antibody,MGC117353antibody,MGC131677 antibody,Nuclear ribonucleoprotein particle C1 protein antibody,Nuclear ribonucleoproteinparticle C2 protein antibody,SNRPC antibody
Gene ID 3183
OMIM 164020
UniProt P07910
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. ELISA: Use at an assay dependent dilution. WB: 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 41,43 kDa). Human nuclear HEK 293A lysate (see Abreview). Detects isoforms at molecular weight approximately 41,43 kDa
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (ABIN108591) Western blot of hnRNP-C1/C2 on Hela extracts
 image for anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (ABIN108591) anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody (Image 2)
Product cited in: Ertel, Brunner, Semler: "Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates." in: Journal of virology, Vol. 84, Issue 9, pp. 4229-42, 2010 (PubMed).

Nicolas, Alazard-Dany, Biollay, Arata, Jolinon, Kuhn, Ferro, Weller, Epstein, Salvetti, Greco: "Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments." in: Journal of virology, Vol. 84, Issue 17, pp. 8871-87, 2010 (PubMed).

Brunner, Ertel, Rozovics, Semler: "Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins." in: Virology, Vol. 400, Issue 2, pp. 240-7, 2010 (PubMed).

Mosessian, Avliyakulov, Mulholland, Boontheung, Loo, Wu: "Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex." in: The Journal of biological chemistry, Vol. 284, Issue 44, pp. 30159-66, 2009 (PubMed).

Herrmann, Pably, Eckerich, Bedford, Fackelmayer: "Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family." in: Journal of cell science, Vol. 122, Issue Pt 5, pp. 667-77, 2009 (PubMed).

Barrandon, Bonnet, Nguyen, Labas, Bensaude: "The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes." in: Molecular and cellular biology, Vol. 27, Issue 20, pp. 6996-7006, 2007 (PubMed).

Baird, Lewis, Turcotte, Holcik: "A search for structurally similar cellular internal ribosome entry sites." in: Nucleic acids research, Vol. 35, Issue 14, pp. 4664-77, 2007 (PubMed).

Kuyumcu-Martinez, Wang, Cooper: "Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation." in: Molecular cell, Vol. 28, Issue 1, pp. 68-78, 2007 (PubMed).

Fu, Collins: "Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation." in: Molecular cell, Vol. 28, Issue 5, pp. 773-85, 2007 (PubMed).

Watson, Blanch, Lin, Ohh, Irwin: "Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34096-103, 2006 (PubMed).

Lin, Yen: "A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein." in: RNA (New York, N.Y.), Vol. 12, Issue 8, pp. 1486-93, 2006 (PubMed).

Dreyfuss, Choi, Adam: "Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies." in: Molecular and cellular biology, Vol. 4, Issue 6, pp. 1104-14, 1984 (PubMed).