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Details for Product No. ABIN108619

Transportin 1 (TNPO1) antibody

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Antigen
Synonyms KPNB2, TRN, MIP, IPO2, MIP1, Kpnb2, AU021749, D13Ertd688e, mip1, zgc:100858, TNPO1, ATTRN1, F12A24.13, F12A24_13, TRANSPORTIN 1, transportin 1, DKFZp469O204
Reactivity
»Alternatives Mouse (Murine), Rabbit, Human, Monkey
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB), Immunoprecipitation (IP)
Pubmed 6 references available
Catalog no. ABIN108619
Quantity 0.1 mL
Price
576.05 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 6 Business Days
Immunogen Recombinant his tagged transportin 1 (Human)
Myeloma Fusion Partners: SP2/0
Clone D45
Isotype IgG1
Specificity Human transportin1. Detects a band of approximately 90 kDa. Cross reacts with monkey & rabbit
Characteristics Mouse Anti-Transportin 1 [D45]
Purification Protein A
Alternative Name Transportin 1
Gene ID 238799
OMIM 602901
UniProt Q8BFY9
Research Area Signaling
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try Flow Cyt: Use 1µg for 106 cells. ICC/IF: Use a concentration of 5 µg/mL IHC-P: Use a concentration of 1 µg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. WB: 1:8000. Detects a band of approximately 93 kDa (predicted molecular weight: 107 kDa)
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS 0.1% sodium azide
Preservative Sodium azide
Storage 4 °C
Product cited in: Siomi, Eder, Kataoka et al.: "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins." in: The Journal of cell biology, Vol. 138, Issue 6, pp. 1181-92, 1997 (PubMed).

Favre, Camps, Arod et al.: "Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation." in: Proteomics, Vol. 8, Issue 21, pp. 4560-76, 2008 (PubMed).

Chen, Shao, Cobos et al.: "4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 116, Issue 1, pp. 206-15, 2010 (PubMed).

Janiszewska, De Vito, Le Bitoux et al.: "Transportin regulates nuclear import of CD44." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30548-57, 2010 (PubMed).

Brelstaff, Lashley, Holton et al.: "Transportin1: a marker of FTLD-FUS." in: Acta neuropathologica, Vol. 122, Issue 5, pp. 591-600, 2011 (PubMed).

Yu, Boyce, Wands et al.: "Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4834-9, 2012 (PubMed).

Alternatives for antigen "Transportin 1 (TNPO1)", type "Antibodies"
Hosts (33), (12), (3), (1)
Reactivities (47), (31), (28), (19), (15), (12), (6), (3), (3), (3), (3), (2)
Applications (36), (18), (15), (11), (10), (9), (7), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (2), (1), (1), (1), (1)
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