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Transportin 1 antibody (TNPO1)

Details for Product anti-TNPO1 Antibody No. ABIN108620, Supplier: Log in to see
Antigen
  • TNPO1
  • ATTRN1
  • F12A24.13
  • F12A24_13
  • TRANSPORTIN 1
  • transportin 1
  • DKFZp469O204
  • mip1
  • zgc:100858
  • JC310
  • MIP1
  • SIN1
  • SIN1b
  • SIN1g
  • IPO2
  • KPNB2
  • MIP
  • TRN
  • AU021749
  • D13Ertd688e
  • Kpnb2
  • Mip1
  • Znf667
  • transportin 1
  • major intrinsic protein of lens fiber a
  • mitogen-activated protein kinase associated protein 1
  • zinc finger protein 667
  • TNPO1
  • tnpo1
  • TRN1
  • mipa
  • MAPKAP1
  • Tnpo1
  • Zfp667
Alternatives
anti-Mouse (Murine) Transportin 1 antibody for Flow Cytometry
Reactivity
Mouse (Murine), Rabbit, Human, Monkey
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24
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2
1
1
1
Host
Mouse
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28
3
Clonality (Clone)
Monoclonal ()
Conjugate
This Transportin 1 antibody is un-conjugated
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7
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
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41
40
37
30
13
9
5
5
3
2
2
2
Options
Supplier
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Immunogen Recombinant his tagged transportin1 (Human)
Clone D45
Isotype IgG1
Purification Protein A
Alternative Name Transportin 1 (TNPO1 Antibody Abstract)
Background Synonyms:
Importin beta 2 antibody,IPO 2 antibody,IPO2 antibody,Karyopherin (importin) beta 2antibody,Karyopherin beta 2 antibody,KPN B2 antibody,KPNB 2 antibody,KPNB2 antibody,M9 interacting proteinantibody,M9 region interacting protein antibody,M9 region interaction protein antibody,M9-interacting proteinantibody,MIP 1 antibody,MIP antibody,MIP1 antibody,TNPO 1 antibody,TNPO1 antibody,Transportinantibody,Transportin-1 antibody,Transportin1 antibody,TRN antibody
Gene ID 3842, 238799
OMIM 602901
UniProt Q8BFY9
Research Area Signaling
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, Flow Cyt: Use 1 μg for 106 cells. ICC/IF: Use a concentration of 5 μg/mL. IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. WB: 1:800. Detects a band of approximately 93 kDa (predicted molecular weight: 107 kDa)
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Transportin 1 antibody (TNPO1) (ABIN108620) Western blot for anti-Transportin1 on HeLa cell extracts
 image for anti-Transportin 1 antibody (TNPO1) (ABIN108620) anti-Transportin 1 (TNPO1) antibody (Image 2)
 image for anti-Transportin 1 antibody (TNPO1) (ABIN108620) anti-Transportin 1 (TNPO1) antibody (Image 3)
Product cited in: Yu, Boyce, Wands, Bond, Bertozzi, Kohler: "Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4834-9, 2012 (PubMed).

Brelstaff, Lashley, Holton, Lees, Rossor, Bandopadhyay, Revesz: "Transportin1: a marker of FTLD-FUS." in: Acta neuropathologica, Vol. 122, Issue 5, pp. 591-600, 2011 (PubMed).

Gu, Tsuji, Jarboui, Yeo, Sheehy, Hall, Gautier: "Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import." in: Retrovirology, Vol. 8, pp. 17, 2011 (PubMed).

Chen, Shao, Cobos, Wang, Gao: "4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 116, Issue 1, pp. 206-15, 2010 (PubMed).

Janiszewska, De Vito, Le Bitoux, Fusco, Stamenkovic: "Transportin regulates nuclear import of CD44." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30548-57, 2010 (PubMed).

Favre, Camps, Arod, Chabert, Rommel, Pasquali: "Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation." in: Proteomics, Vol. 8, Issue 21, pp. 4560-76, 2008 (PubMed).

Background publications Siomi, Eder, Kataoka, Wan, Liu, Dreyfuss: "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins." in: The Journal of cell biology, Vol. 138, Issue 6, pp. 1181-92, 1997 (PubMed).