Lamin B2 antibody (LMNB2) (C-Term)

Details for Product anti-LMNB2 Antibody No. ABIN108634, Supplier: Log in to see
Antigen
  • lmnb2-a
  • LMNB2
  • lmn2
  • lamb2
  • Lamin-L(II)
  • LOC100136040
  • im:7142331
  • lamin
  • wu:fb94e05
  • wu:fb95e12
  • wu:fc15d06
  • wu:fc49h03
  • lamin-b2
  • lmnb2
  • LAMB2
  • LMN2
  • RGD1563803
  • lamin B2
  • lmnb2-a
  • LMNB2
  • lmnb2
  • LOC100136040
  • lmnb2-b
  • Lmnb2
Alternatives
anti-Mouse (Murine) Lamin B2 antibody for Immunocytochemistry
Epitope
C-Term
15
6
3
3
2
2
2
2
2
1
1
1
1
Reactivity
Hamster, Human, Mouse (Murine), Xenopus laevis, Zebrafish (Danio rerio)
80
42
30
12
9
5
5
5
4
4
2
2
2
2
2
2
2
2
1
1
Host
Mouse
58
26
Clonality (Clone)
Monoclonal ()
Conjugate
This Lamin B2 antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
68
24
16
15
14
14
13
10
8
6
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Detergent insoluble fraction of potoroo cell line PtK1.
Clone LN43
Isotype IgG1
Specificity Reacts with an epitope located in the C-terminal part of lamin B2.
Purification Purified
Alternative Name Lamin B2 (LMNB2 Antibody Abstract)
Background Synonyms:
Lamin B1 antibody,Lamin B2 antibody,LMN antibody,LMN B2 antibody,LMN2 antibody,LMNBantibody,LMNB1 antibody,LMNB2 antibody
Gene ID 84823, 16907
OMIM 150341
UniProt P21619
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, ICC: 1/400. Flow Cyt: Use 1 μg for 106 cells. IHC-Fr: 1/1 - 1/1. (when used with an avidin-biotinylated HRP complex as detection agent). WB: 1/100 - 1/1000. Detects a band of approximately 65-67 kDa.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody in PBS containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
 image for anti-Lamin B2 (LMNB2) (C-Term) antibody (ABIN108634) Immunostaining of lamin antibodies (c) is Lamin B2 (clone LN43), with human epidermis.
Product cited in: Tsai, Lee, Lin: "Ribosome distribution in HeLa cells during the cell cycle." in: PLoS ONE, Vol. 7, Issue 3, pp. e32820, 2012 (PubMed).

Shimi, Butin-Israeli, Adam, Hamanaka, Goldman, Lucas, Shumaker, Kosak, Chandel, Goldman: "The role of nuclear lamin B1 in cell proliferation and senescence." in: Genes & development, Vol. 25, Issue 24, pp. 2579-93, 2011 (PubMed).

Taimen, Pfleghaar, Shimi, Möller, Ben-Harush, Erdos, Adam, Herrmann, Medalia, Collins, Goldman, Goldman: "A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20788-93, 2010 (PubMed).

Ishimoto, Nakamura, Tachibana, Yamasaki, Ota, Hirano, Tanaka, Hamakubo, Sakai, Kodama, Doi: "Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22195-205, 2009 (PubMed).

Mackay, Elgort, Ullman: "The nucleoporin Nup153 has separable roles in both early mitotic progression and the resolution of mitosis." in: Molecular biology of the cell, Vol. 20, Issue 6, pp. 1652-60, 2009 (PubMed).

Hisatsune, Nakayama, Isomoto, Kurazono, Mukaida, Mukhopadhyay, Azuma, Yamaoka, Sap, Yamasaki, Yahiro, Moss, Hirayama et al.: "Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 5017-27, 2008 (PubMed).

Koutsami, Tsantoulis, Kouloukoussa, Apostolopoulou, Pateras, Spartinou, Drougou, Evangelou, Kittas, Bartkova, Bartek, Gorgoulis: "Centrosome abnormalities are frequently observed in non-small-cell lung cancer and are associated with aneuploidy and cyclin E overexpression." in: The Journal of pathology, Vol. 209, Issue 4, pp. 512-21, 2006 (PubMed).

Tsai, Wang, Heidinger, Shumaker, Adam, Goldman, Zheng: "A mitotic lamin B matrix induced by RanGTP required for spindle assembly." in: Science (New York, N.Y.), Vol. 311, Issue 5769, pp. 1887-93, 2006 (PubMed).

Krohne: "Lamins." in: Methods in cell biology, Vol. 78, pp. 573-96, 2005 (PubMed).

Background publications Broers, Machiels, Kuijpers, Smedts, van den Kieboom, Raymond, Ramaekers: "A- and B-type lamins are differentially expressed in normal human tissues." in: Histochemistry and cell biology, Vol. 107, Issue 6, pp. 505-17, 1997 (PubMed).

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