POU3F2 antibody (AA 214-362)

Catalog No. ABIN1098110

Product Details anti-POU3F2 Antibody

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Binding Specificity: AA 214-362

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This POU3F2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human POU3F2 (AA: 214-362) expressed in E. coli.

Clone: 6H12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-POU3F2 antibody (ABIN1098110)

Goodall, Carreira, Denat, Kobi, Davidson, Nuciforo, Sturm, Larue, Goding: "Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells." in: Cancer research, Vol. 68, Issue 19, pp. 7788-94, (2008) (PubMed).

Cobrinik, Francis, Abramson, Lee: "Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells." in: Molecular cancer, Vol. 5, pp. 72, (2007) (PubMed).

Target Details for POU3F2

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Alternative Name: POU3F2 (POU3F2 Products)

Synonyms: BRN2 antibody, N-Oct3 antibody, OCT7 antibody, OTF-7 antibody, OTF7 antibody, POUF3 antibody, brn-2 antibody, oct-7 antibody, XlPOU3 antibody, pou3f2 antibody, pou3f2-A antibody, pou3f4 antibody, 9430075J19Rik antibody, A230098E07Rik antibody, Brn-2 antibody, Brn2 antibody, Otf7 antibody, XLPOU3b antibody, pou47 antibody, zp47 antibody, zp47pou antibody, brn-1.2 antibody, brn1.2 antibody, id:ibd5088 antibody, POU class 3 homeobox 2 antibody, POU class 3 homeobox 2 L homeolog antibody, POU domain, class 3, transcription factor 2 antibody, POU class 3 homeobox 2 S homeolog antibody, POU class 3 homeobox 2b antibody, POU class 3 homeobox 2a antibody, POU3F2 antibody, pou3f2.L antibody, Pou3f2 antibody, pou3f2.S antibody, pou3f2b antibody, pou3f2a antibody

Background:

Description: This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

Aliases: BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7, N-Oct3

Molecular Weight: 46.9 kDa

Gene ID: 5454

HGNC: 5454