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CSNK2A2 antibody (AA 194-350)

CSNK2A2 Reactivity: Human, Mouse WB, ELISA, FACS Host: Mouse Monoclonal 1-00E-01 unconjugated
Catalog No. ABIN1098114
  • Target See all CSNK2A2 Antibodies
    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 194-350
    Reactivity
    • 44
    • 23
    • 12
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 42
    • 2
    Mouse
    Clonality
    • 41
    • 3
    Monoclonal
    Conjugate
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSNK2A2 antibody is un-conjugated
    Application
    • 30
    • 25
    • 10
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. coli.
    Clone
    1-00E-01
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Chemnitz, Pieper, Grüttner, Hauber: "Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression." in: European journal of immunology, Vol. 39, Issue 1, pp. 267-79, (2009) (PubMed).

    Schäfer, Götz, Dudek, Hessenauer, Matti, Montenarh: "KIF5C: a new binding partner for protein kinase CK2 with a preference for the CK2alpha' subunit." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 2, pp. 339-49, (2009) (PubMed).

  • Target
    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))
    Alternative Name
    CSNK2A2 (CSNK2A2 Products)
    Synonyms
    CK2A2 antibody, CSNK2A1 antibody, 1110035J23Rik antibody, C77789 antibody, CK2 antibody, CSNK2A2 antibody, ck2a2 antibody, csnk2a1 antibody, wu:fi09h12 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2, alpha prime polypeptide antibody, casein kinase 2 alpha 2 L homeolog antibody, casein kinase 2, alpha prime polypeptide a antibody, CSNK2A2 antibody, Csnk2a2 antibody, csnk2a2.L antibody, csnk2a2 antibody, csnk2a2a antibody
    Background

    Description: Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

    Aliases: CK2A2, CSNK2A1, FLJ43934

    Molecular Weight
    41.2 kDa
    Gene ID
    1459
    HGNC
    1459
    Pathways
    SARS-CoV-2 Protein Interactome
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