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NEFH antibody (AA 968-1020)

NEFH Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 8H10 unconjugated
Catalog No. ABIN1098127
  • Target See all NEFH Antibodies
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Binding Specificity
    • 16
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020
    Reactivity
    • 108
    • 82
    • 64
    • 48
    • 28
    • 28
    • 12
    • 12
    • 9
    • 9
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 66
    • 56
    • 10
    Mouse
    Clonality
    • 82
    • 50
    Monoclonal
    Conjugate
    • 89
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFH antibody is un-conjugated
    Application
    • 89
    • 43
    • 37
    • 28
    • 27
    • 24
    • 24
    • 16
    • 14
    • 13
    • 13
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. coli.
    Clone
    8H10
    Isotype
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • Application Notes
    ELISA: Propose dilution 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • Target
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Alternative Name
    NEFH (NEFH Products)
    Synonyms
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    Background

    Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. , ,

    Aliases: NFH

    Molecular Weight
    112.4 kDa
    Gene ID
    4744
    HGNC
    4744
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