Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) antibody
Reactivity: Mouse
IHC, WB, IF/ICC
Host: Mouse
Monoclonal
S178A-9
unconjugated
1 image
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- Target
- Cav3.1 Ca2+ Channel
- Binding Specificity
- AA 2052-2172, C-Term
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
- Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)
- Purpose
- Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody
- Specificity
- This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.
- Cross-Reactivity
- Human, Mouse, Rat
- Cross-Reactivity (Details)
- No cross Reactivity with Cav3.2
- Purification
- Purified by Protein G affinity chromatography.
- Immunogen
- Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).
- Clone
- S178A-9
- Isotype
- IgG1
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- Application Notes
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Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain membranes. - Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
- Dilute in PBS or medium which is identical to that used in the assay system.
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- This antibody is stable for at least one (1) year at -20°C.
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- Target
- Cav3.1 Ca2+ Channel
- Alternative Name
- Cav3.1 Ca+2 Channel
- Background
- Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.
- NCBI Accession
- NP_001106284
- UniProt
- Q9WUT2
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