Hexosaminidase A Protein (HEXA) (His tag)
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- Target See all Hexosaminidase A (HEXA) Proteins
- Hexosaminidase A (HEXA)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Hexosaminidase A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product HEXA Protein
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Hexosaminidase A (HEXA) (AA 1-529) protein (GST tag)
HEXA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hexosaminidase A (HEXA) (AA 89-529) protein (His tag)Crystallography grade HEXA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Hexosaminidase A (HEXA) (AA 89-528) protein (His tag)Crystallography grade HEXA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Hexosaminidase A (HEXA) (AA 319-528) (Active) protein (His tag)HEXA Origin: Mouse Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Hexosaminidase A (HEXA) protein (Myc-DYKDDDDK Tag)HEXA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: beta-hexosaminidase subunit alpha, TSD, hexosaminidase A
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M UREA, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Hexosaminidase A (HEXA)
- Alternative Name
- HEXA (HEXA Products)
- Synonyms
- TSD Protein, fc04h11 Protein, wu:fc04h11 Protein, wu:fv09f06 Protein, si:dkey-35i22.2 Protein, HEXA Protein, Hex-1 Protein, zgc:112084 Protein, hexosaminidase subunit alpha Protein, hexosaminidase B (beta polypeptide) Protein, CUGBP Elav-like family member 6 Protein, hexosaminidase A Protein, hexosaminidase A (alpha polypeptide) Protein, beta-hexosaminidase subunit alpha-like Protein, HEXA Protein, hexb Protein, CELF6 Protein, Hexa Protein, hexa Protein, LOC100228061 Protein
- Background
- HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Recombinant human HEXA protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 52.9 kDa (464aa)
- NCBI Accession
- NP_000511
- Pathways
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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