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IGLL1 Protein (His tag)

IGLL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN1098784
  • Target See all IGLL1 Proteins
    IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IGLL1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product IGLL1 Protein
  • Comment

    Synonyms: Immunoglobulin lambda-like polypeptide 1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
    Alternative Name
    IGLL1 (IGLL1 Products)
    Synonyms
    14.1 Protein, AGM2 Protein, CD179b Protein, IGL1 Protein, IGL5 Protein, IGLJ14.1 Protein, IGLL Protein, IGO Protein, IGVPB Protein, VPREB2 Protein, IGLV Protein, IGLL1 Protein, MGC151892 Protein, Igll1 Protein, BB139905 Protein, Igl-5 Protein, Igll Protein, Lambda5 Protein, immunoglobulin lambda like polypeptide 1 Protein, immunoglobulin lambda-like polypeptide 1 Protein, IGLL1 Protein, Igll1 Protein
    Background
    The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human IGLL1protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    21.5 kDa (199aa)
    NCBI Accession
    NP_064455
    Pathways
    Regulation of Cell Size
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