You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 830-949) antibody

Details for Product No. ABIN1105171, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2, 1700019L09Rik, Mlp2, Mrp3
AA 830-949
(16), (15), (12), (4), (2), (2), (1), (1), (1), (1)
(72), (18), (17), (1), (1)
(52), (12), (10)
Clonality (Clone)
Monoclonal ()
(4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
(54), (35), (21), (18), (12), (11), (8), (7), (6), (2), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein.
Clone M3II-21
Isotype IgG2b
Specificity This Monoclonal antibody M3II-21 reacts with an internal epitope of MRP3, a 190-200 kDa transmembrane protein that is closely related to the multidrug resistance protein MRP1. It does not cross-react with the Human MDR1, MRP1, MRP2 or MRP5 gene products.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Supernatant
Alternative Name ABCC3 / CMOAT2 / MRP3 (ABCC3 Antibody Abstract)
Background Human multidrug-resistance protein (MRP) gene family is composed of multiple members including MRP 1, MRP 2 or cMOAT and four other homologous genes called MRP 3, MRP 4, MRP 5 and MRP 6. Canalicular Multi Organic Anion Transporter 2 / Multidrug Resistance Associated Protein 3 (cMOAT 2 / MRP 3) has a molecular weight of 190-200 kD. MRP3 is closest to MRP1 with 58 % amino acid identity. MRP 3 has been shown to be mainly expressed in the liver, colon, intestine, adrenal gland and, to a lower extent, in several other tissues.Synonyms: Canalicular multispecific organic anion transporter 2, MLP2, Multidrug resistance-associated protein 3
Gene ID 8714
NCBI Accession NP_001137542
UniProt O15438
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg Ig /ml
Buffer 0.09 % Sodium Azide 0.9 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Kool, van der Linden, de Haas et al.: "MRP3, an organic anion transporter able to transport anti-cancer drugs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 12, pp. 6914-9, 1999 (PubMed).

Kool, de Haas, Scheffer et al.: "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines." in: Cancer research, Vol. 57, Issue 16, pp. 3537-47, 1997 (PubMed).

Catalog No. ABIN1105171
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)