ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 830-949) antibody

Details for Product No. ABIN1105171
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Antigen
Synonyms ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2, 1700019L09Rik, Mlp2, Mrp3
Epitope
AA 830-949
(8), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(56), (26), (25), (12)
Host
Mouse
(42), (14), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(36), (20), (18), (11), (11), (9), (8), (6), (5)
Pubmed 2 references available
Catalog no. ABIN1105171
Quantity 1 mL
Price
588.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein.
Clone M3II-21
Isotype IgG2b
Specificity This Monoclonal antibody M3II-21 reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. It does not cross-react with the Human MDR1, MRP1, MRP2 or MRP5 gene products.
Purification Supernatant
Alternative Name ABCC3 / CMOAT2 / MRP3
Background Human multidrug-resistance protein (MRP) gene family is composed of multiple members including MRP 1, MRP 2 or cMOAT and four other homologous genes called MRP 3, MRP 4, MRP 5 and MRP 6. Canalicular Multi Organic Anion Transporter 2 / Multidrug Resistance Associated Protein 3 (cMOAT 2 / MRP 3) has a molecular weight of 190-200 kD. MRP3 is closest to MRP1 with 58% amino acid identity. MRP 3 has been shown to be mainly expressed in the liver, colon, intestine, adrenal gland and, to a lower extent, in several other tissues.
Alternate names: Canalicular multispecific organic anion transporter 2, MLP2, Multidrug resistance- associated protein 3
Gene ID 8714
NCBI Accession NP_001137542.1
UniProt O15438
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg Ig /ml
Buffer 0.09% Sodium Azide 0.7% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Kool, de Haas, Scheffer et al.: "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines." in: Cancer research, Vol. 57, Issue 16, pp. 3537-47, 1997 (PubMed).

Kool, van der Linden, de Haas et al.: "MRP3, an organic anion transporter able to transport anti-cancer drugs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 12, pp. 6914-9, 1999 (PubMed).

Hosts (42), (14), (2)
Reactivities (56), (26), (25), (12)
Applications (36), (20), (18), (11), (11), (9), (8), (6), (5)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (8), (3), (2), (2), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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