You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 830-949) antibody

Details for Product No. ABIN1105172, Supplier: Log in to see
Antigen
  • ABC31
  • EST90757
  • MLP2
  • MOAT-D
  • MRP3
  • cMOAT2
  • 1700019L09Rik
  • Mlp2
  • Mrp3
Epitope
AA 830-949
16
15
12
3
2
2
1
1
1
Reactivity
Human
70
18
16
1
1
Host
Mouse
51
10
10
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
52
34
20
18
12
10
6
6
5
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein.
Clone M3II-9
Isotype IgG1
Specificity This Monoclonal antibody M3II-9 reacts with an internal epitope of MRP3, a 190-200 kDa transmembrane protein that is closely related to the multidrug resistance protein MRP1. It does not cross-react with the Human MDR1, MRP1, MRP2 or MRP5 gene products.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Supernatant
Alternative Name ABCC3 / CMOAT2 / MRP3 (ABCC3 Antibody Abstract)
Background Human multidrug-resistance protein (MRP) gene family is composed of multiple members including MRP 1, MRP 2 or cMOAT and four other homologous genes called MRP 3, MRP 4, MRP 5 and MRP 6. Canalicular Multi Organic Anion Transporter 2 / Multidrug Resistance Associated Protein 3 (cMOAT 2 / MRP 3) has a molecular weight of 190-200 kD. MRP3 is closest to MRP1 with 58 % amino acid identity. MRP 3 has been shown to be mainly expressed in the liver, colon, intestine, adrenal gland and, to a lower extent, in several other tissues.Synonyms: Canalicular multispecific organic anion transporter 2, MLP2, Multidrug resistance-associated protein 3
Gene ID 8714
NCBI Accession NP_001137542
UniProt O15438
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg Ig /ml
Buffer 0.09 % Sodium Azide 0.9 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Peng, Yanagida, Chen et al.: "Ellipsoidal TiO2 hierarchitectures with enhanced photovoltaic performance." in: Chemistry (Weinheim an der Bergstrasse, Germany), Vol. 18, Issue 17, pp. 5269-74, 2012 (PubMed).

Scheffer, Kool, Heijn et al.: "Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies." in: Cancer research, Vol. 60, Issue 18, pp. 5269-77, 2000 (PubMed).

Kool, van der Linden, de Haas et al.: "MRP3, an organic anion transporter able to transport anti-cancer drugs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 12, pp. 6914-9, 1999 (PubMed).

Kool, de Haas, Scheffer et al.: "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines." in: Cancer research, Vol. 57, Issue 16, pp. 3537-47, 1997 (PubMed).