Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta)

Details for Product anti-ACTA2 Antibody No. ABIN1105232, Supplier: Log in to see
Antigen
  • ASMA
  • SMactin
  • a-sma
  • aat6
  • actsa
  • mymy5
  • sm-actin
  • ACTA2
  • actc1
  • ACT-4
  • AAT6
  • ACTSA
  • MYMY5
  • 0610041G09Rik
  • Actvs
  • SMalphaA
  • a-SMA
  • alphaSMA
  • wu:fb63d03
  • asma
  • actin, alpha 2, smooth muscle, aorta
  • acta2
  • ACTA2
  • Acta2
Alternatives
anti-Monkey Smooth Muscle Actin antibody for ELISA
Reactivity
Human, Monkey
267
138
130
63
51
42
33
21
10
10
8
7
5
5
4
4
2
2
2
2
1
1
Host
Mouse
158
100
15
Clonality (Clone)
Monoclonal ()
Conjugate
This Smooth Muscle Actin antibody is un-conjugated
9
5
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
161
112
91
75
52
47
17
17
13
6
4
3
3
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Clone 4F4
Isotype IgG1
Specificity Recognizes ACTA2
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey.
Purification Ascites
Background The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
Molecular Weight 42 kDa
Gene ID 59
Pathways Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
ELISA image for anti-Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta) (ABIN1105232) anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody
Western Blotting (WB) image for anti-Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta) (ABIN1105232) anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta) (ABIN1105232) anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta) (ABIN1105232) anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody (Image 4)
Background publications Guo, Pannu, Tran-Fadulu, Papke, Yu, Avidan, Bourgeois, Estrera, Safi, Sparks, Amor, Ades, McConnell, Willoughby, Abuelo, Willing, Lewis, Kim, Scherer, Tung, Ahn, Buja, Raman, Shete, Milewicz: "Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections." in: Nature genetics, Vol. 39, Issue 12, pp. 1488-93, 2007 (PubMed).

Salas, Bartoli, Deville, Gaudart, Fina, Calisti, Bollini, Curvale, Gentet, Duffaud, Figarella-Branger, Bouvier: "Ezrin and alpha-smooth muscle actin are immunohistochemical prognostic markers in conventional osteosarcomas." in: Virchows Archiv : an international journal of pathology, Vol. 451, Issue 6, pp. 999-1007, 2007 (PubMed).