Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) antibody

Details for Product No. ABIN1105244
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Antigen
Synonyms Nyw1, 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, DCAF3, WDR94
Epitope
N-Term
(19), (10), (2), (2), (1)
Reactivity
Mouse (Murine)
(49), (44), (29), (13), (12), (1)
Host
Rabbit
(56), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Western Blotting (WB)
(47), (31), (26), (14), (10), (6), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN1105244
Quantity 0.2 mL
Price
555.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Specificity This antibody reacts with Mouse 120 kDa Ambra1 protein.
Purification Serum
Alternative Name AMBRA1
Background Alternate names: Activating molecule in BECN1-regulated autophagy protein 1, KIAA1736
Gene ID 55626
NCBI Accession NP_060219.2
Research Area Cancer, Autophagy, Neurogenesis
Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore in distilled water.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Di Bartolomeo, Corazzari, Nazio et al.: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, 2010 (PubMed).

Armstrong, Corazzari, Martin et al.: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, 2011 (PubMed).

Pagliarini, Wirawan, Romagnoli et al.: "Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response." in: Cell death and differentiation, Vol. 19, Issue 9, pp. 1495-504, 2012 (PubMed).

Hosts (56), (1)
Reactivities (49), (44), (29), (13), (12), (1)
Applications (47), (31), (26), (14), (10), (6), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (19), (10), (2), (2), (1)
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