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AKT1 antibody (AA 461-477)
AKT1
Reactivity: Human, Chicken
WB
Host: Mouse
Monoclonal
IML-26
unconjugated
Product Details anti-AKT1 Antibody
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Target
See all AKT1 Antibodies
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
Binding Specificity
All epitopes for AKT1 antibodies
AA 461-477
Reactivity
All reactivities for AKT1 antibodies
Human, Chicken
Host
All hosts for AKT1 antibodies
Mouse
Clonality
All clonalities for AKT1 antibodies
Monoclonal
Conjugate
All conjugates for AKT1 antibodies
This AKT1 antibody is un-conjugated
Application
All applications for AKT1 antibodies
Western Blotting (WB)
Specificity
This antibody reacts to AKT1 / PKB.
Purification
Affinity chromatography
Immunogen
Synthetic peptide corresponding to amino acids 461-477 of human PKBalpha/Akt1.
Clone
IML-26
Isotype
IgG1
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Discover our top product AKT1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore with 1.2 % sodium acetate or neutral PBS
Concentration
0,1 mg/mL
Buffer
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for AKT1
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Target
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
Alternative Name
AKT1 / PKB (AKT1 Products )
Synonyms
AKT antibody, CWS6 antibody, PKB antibody, PKB-ALPHA antibody, PRKBA antibody, RAC antibody, RAC-ALPHA antibody, Akt antibody, Rac antibody, PKB/Akt antibody, PKBalpha antibody, AKT/PKB antibody, AKT1 antibody, Akt/PKB antibody, Akt1 antibody, CG4006 antibody, D-Akt antibody, DAKT1 antibody, DAKT1/PKB antibody, DAkt antibody, DAkt1 antibody, DPKB antibody, DRAC-PK antibody, DRAC-PK66 antibody, DRAC-PK85 antibody, Dakt antibody, Dakt1 antibody, Dmel\\CG4006 antibody, Dpkb antibody, PKB/AKT antibody, PKB/dAKT antibody, RacPK antibody, akt antibody, akt1 antibody, dAKT antibody, dAKT/dPKB antibody, dAKT1 antibody, dAkt antibody, dAkt/PKB antibody, dAkt1 antibody, dPKB antibody, dakt antibody, dakt1 antibody, l(3)04226 antibody, l(3)89Bq antibody, p-Akt antibody, pAkt antibody, ACT-5 antibody, akt-1 antibody, pkb antibody, v-akt antibody, v-akt1 antibody, xAct antibody, ATAKT1 antibody, F18A8.2 antibody, F18A8_2 antibody, K+ transporter 1 antibody, POTASSIUM TRANSPORTER antibody, AKT serine/threonine kinase 1 antibody, thymoma viral proto-oncogene 1 antibody, CG4006 gene product from transcript CG4006-RE antibody, actin beta antibody, v-akt murine thymoma viral oncogene homolog 1 S homeolog antibody, v-akt murine thymoma viral oncogene homolog 1 antibody, K+ transporter 1 antibody, Serine/threonine-protein kinase akt-1 antibody, AKT1 antibody, Akt1 antibody, ACTB antibody, akt1.S antibody, akt1 antibody, KT1 antibody, akt-1 antibody
Background
PKBalpha also knows as V-AKT murine thymoma vial oncogene homolog 1(ATK1). AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.Synonyms: Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase
Gene ID
207
NCBI Accession
NP_001014431
UniProt
P31749
Pathways
PI3K-Akt Signaling , RTK Signaling , TCR Signaling , AMPK Signaling , Interferon-gamma Pathway , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Response to Water Deprivation , Regulation of Actin Filament Polymerization , Carbohydrate Homeostasis , Glycosaminoglycan Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Regulation of Cell Size , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Protein targeting to Nucleus , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Negative Regulation of intrinsic apoptotic Signaling , Thromboxane A2 Receptor Signaling , Signaling of Hepatocyte Growth Factor Receptor , Positive Regulation of fat Cell Differentiation , VEGFR1 Specific Signals , VEGF Signaling , Warburg Effect
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