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ALPL antibody

ALPL Reactivity: Human WB, IHC (p), FACS, EIA Host: Mouse Monoclonal 2F4 unconjugated
Catalog No. ABIN1105293
  • Target See all ALPL Antibodies
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    Reactivity
    • 85
    • 50
    • 17
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 83
    • 18
    • 1
    • 1
    Mouse
    Clonality
    • 83
    • 20
    Monoclonal
    Conjugate
    • 61
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALPL antibody is un-conjugated
    Application
    • 75
    • 43
    • 27
    • 17
    • 13
    • 13
    • 13
    • 11
    • 11
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    Recognizes Human Alkaline phosphatase / ALPL. Other species not tested.
    Purification
    Purified
    Clone
    2F4
    Isotype
    IgG1
    Top Product
    Discover our top product ALPL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    Alternative Name
    Alkaline Phosphatase / ALPL (ALPL Products)
    Synonyms
    ALP antibody, iap antibody, alpl antibody, AP-TNAP antibody, APTNAP antibody, HOPS antibody, TNAP antibody, TNSALP antibody, Akp-2 antibody, Akp2 antibody, PHOA antibody, TNS-AP antibody, alkaline phosphatase, liver/bone/kidney L homeolog antibody, alkaline phosphatase, liver/bone/kidney antibody, alkaline phosphatase, intestinal, gene 2 antibody, alkaline phosphatase, liver/bone/kidney pseudogene antibody, alpl.L antibody, ALPL antibody, alpi.2 antibody, LOC100031702 antibody, Alpl antibody
    Background
    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.Synonyms: AP-TNAP, Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, TNSALP, tissue-nonspecific isozyme
    Molecular Weight
    57.3 kDa
    Gene ID
    249
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