SERPINA1 antibody

Catalog No. ABIN1105314

Product Details anti-SERPINA1 Antibody

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This SERPINA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Purification: Delipidation and defibrination

Immunogen: alpha 1-Anti-Trypsin [Human Plasma]

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with 2.0 mL of deionized water or equivalent.

Concentration: 90.0 mg/mL (prior to lyophilization by refractometry)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide, None

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store vial at 2-8 °C prior to restoration. Restore with 2.0 ml of deionized water (or equivalent). Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid. For extended storage aliquot contents and freeze at -20 °C or below.

References for anti-SERPINA1 antibody (ABIN1105314)

Schachner, Golderer, Sarg, Lindner, Bonaros, Mikuz, Laufer, Werner: "The amounts of alpha 1 antitrypsin protein are reduced in the vascular wall of the acutely dissected human ascending aorta." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 37, Issue 3, pp. 684-90, (2011) (PubMed).

Target Details for SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: alpha-1-Antitrypsin (SERPINA1 Products)

Synonyms: AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, A1A antibody, AAT antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, Pi antibody, Spi1 antibody, MGC64429 antibody, serpina1d antibody, Aps antibody, SERPINA3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, alpha-1-antitrypsin antibody, calumenin antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, SH2B adaptor protein 2 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, LOC100328621 antibody, CALU antibody, Serpina1 antibody, serpina1.S antibody, serpina1 antibody, SPIA5 antibody, Sh2b2 antibody, Calu antibody, serpina1.L antibody

Background: Alpha-1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase.Synonyms: AAT, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1

Gene ID: 9606

UniProt: P01009