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AMD1 antibody (C-Term)

AMD1 Reactivity: Human, Mouse, Rat WB, IHC (p), IF, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1105345
  • Target See all AMD1 Antibodies
    AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))
    Binding Specificity
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 13
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 2
    Rabbit
    Clonality
    • 31
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMD1 antibody is un-conjugated
    Application
    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody detects AMD1 (C-term). No cross reactivity with other proteins.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Immunogen affinity purified
    Immunogen
    Synthetic peptide corresponding to a sequence at the C-terminal of human SAMDC .Remarks: Sequence is identical to the related mouse and rat sequence.
    Isotype
    IgG
    Top Product
    Discover our top product AMD1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    Preservative
    Sodium azide, Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))
    Alternative Name
    AMD1 (AMD1 Products)
    Synonyms
    ADOMETDC antibody, AMD antibody, SAMDC antibody, Amd1a antibody, Amd1b antibody, AMD1 antibody, AdoMetDC antibody, amd antibody, samdc antibody, fb26e03 antibody, si:ch211-257g8.2 antibody, wu:fb26e03 antibody, zgc:55614 antibody, 1 antibody, Amd-1 antibody, SAMDC 1 antibody, adoMetDC1 antibody, CG5029 antibody, Dmel\\CG5029 antibody, l(2)31Dc antibody, l(2)31Dd antibody, l(2)31De antibody, F16B3.10 antibody, F16B3_10 antibody, S-ADENOSYLMETHIONINE DECARBOXYLASE antibody, S-adenosylmethionine decarboxylase antibody, adenosylmethionine decarboxylase 1 antibody, S-adenosylmethionine decarboxylase 1 antibody, S-adenosyl methionine decarboxylase 2 antibody, adenosylmethionine decarboxylase 1 L homeolog antibody, S-adenosylmethionine decarboxylase antibody, AMD1 antibody, Amd1 antibody, amd1 antibody, sam2 antibody, amd1.L antibody, SamDC antibody, SAMDC antibody
    Background
    S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.Synonyms: AdoMetDC, S-adenosylmethionine decarboxylase proenzyme, SAMDC
    Gene ID
    262
    NCBI Accession
    NP_001625
    UniProt
    P17707
    Pathways
    Ribonucleoside Biosynthetic Process
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