Annexin V antibody (C-Term)

Catalog No. ABIN1105379

Product Details anti-Annexin V Antibody

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin V antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody detects Annexin A5 / ANXA5 near C-term. No cross reactivity with other proteins.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat.

Purification: Immunoaffinity Chromatography.

Immunogen: A synthetic peptide corresponding to a sequence near the C-terminal of Human Annexin V .Remarks: Sequence is identical to the related rat and mouse sequence

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.2 mL of distilled water to a concentration of 0.5 mg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: Annexin A5 / ANXA5 (ANXA5 Products)

Synonyms: anx antibody, anx5 antibody, ANX V antibody, anxa5 antibody, cb989 antibody, wu:fa98f06 antibody, wu:fj10f10 antibody, MGC89158 antibody, ANX5 antibody, ENX2 antibody, PP4 antibody, RPRGL3 antibody, Anx5 antibody, R74653 antibody, LC5 antibody, enx2 antibody, annexin A5 antibody, annexin A5b antibody, Annexin A5 antibody, annexin A5 L homeolog antibody, ANXA5 antibody, anxa5b antibody, anxa5 antibody, Anxa5 antibody, anxa5.L antibody

Background: Annexin V also know as endonnexin II(ENX2),or placental protein 4 (PP4). Endonexin II is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. It has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2 (basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The PP4 cDNA encoded a protein of 320 amino acid residues.A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. PP4 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex,which is involved in the blood coagulation cascade.Synonyms: ANX5, Anchorin CII, Annexin V, Annexin-5, CBP-I, Calphobindin I, ENX2, Endonexin II, Lipocortin V, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha

Gene ID: 308

NCBI Accession: NP_001145

UniProt: P08758

Pathways: Apoptosis