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BIN1 antibody (AA 189-398)

BIN1 Reactivity: Human, Mouse, Rat, Pig, Chicken WB, IHC (p), IHC (fro) Host: Mouse Monoclonal BN-1 unconjugated
Catalog No. ABIN1105531
  • Target See all BIN1 Antibodies
    BIN1 (Bridging Integrator 1 (BIN1))
    Binding Specificity
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-398
    Reactivity
    • 47
    • 23
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Pig, Chicken
    Host
    • 34
    • 12
    • 1
    Mouse
    Clonality
    • 35
    • 12
    Monoclonal
    Conjugate
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIN1 antibody is un-conjugated
    Application
    • 35
    • 22
    • 20
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Recognizes BIN1. No cross reactivity with other proteins.
    Purification
    Affinity Chromatography
    Immunogen
    Recombinant polypeptide containing amino acids 189-398 of Human Bin1.
    Clone
    BN-1
    Isotype
    IgG2b
    Top Product
    Discover our top product BIN1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.2 % Sodium Acetate or neutral PBS.
    Concentration
    0.1 mg/mL
    Buffer
    1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    BIN1 (Bridging Integrator 1 (BIN1))
    Alternative Name
    BIN1 / AMPHL (BIN1 Products)
    Synonyms
    bin1 antibody, MGC53185 antibody, amph2 antibody, amphl antibody, sh3p9 antibody, MGC76187 antibody, cb57 antibody, zgc:86701 antibody, BIN1 antibody, AMPH2 antibody, AMPHL antibody, SH3P9 antibody, ALP-1 antibody, Amphl antibody, BRAMP-2 antibody, bridging integrator 1 antibody, bridging integrator 1 S homeolog antibody, bridging integrator 1b antibody, BIN1 antibody, bin1.S antibody, bin1 antibody, bin1b antibody, Bin1 antibody
    Background
    BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1
    Gene ID
    274, 9606
    UniProt
    O00499
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