Feline Sarcoma Oncogene (FES) antibody

Details for Product No. ABIN1105572
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Antigen
Synonyms FES, c-fps, FPS, AI586313, BB137047, c-fes, RGD1564385
Reactivity
Human
(86), (29), (18), (12), (12), (1), (1), (1)
Host
Mouse
(52), (33), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(74), (46), (18), (10), (10), (5), (4), (3), (2), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1105572
390.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Clone 5A11G5
Isotype IgG1
Specificity Recognizes FES (feline sarcoma oncogene).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name C-Fes
Background FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases. FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain. They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains. FES was originally identified as an oncogene from avian and feline retroviruses. Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Mutations may activate the FES kinase and thereby contribute to cancer. However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.Synonyms: FES, FPS, Proto-oncogene c-Fps, Proto-oncogene tyrosine-protein kinase Fes/Fps
Gene ID 2242
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Feline Sarcoma Oncogene (FES) antibody anti-Feline Sarcoma Oncogene (FES) antibody
Background publications Vitenzon, Mironov, Petrushanskaya: "Functional electrostimulation of muscles as a method for restoring motor functions." in: Neuroscience and behavioral physiology, Vol. 35, Issue 7, pp. 709-14, 2006 (PubMed).

Durfee, Rivard: "Design and simulation of a pneumatic, stored-energy, hybrid orthosis for gait restoration." in: Journal of biomechanical engineering, Vol. 127, Issue 6, pp. 1014-9, 2006 (PubMed).

Delfino, Stevenson, Smithgall: "A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer." in: The Journal of biological chemistry, Vol. 281, Issue 13, pp. 8829-35, 2006 (PubMed).

Noginov, Novak, Grigsby et al.: "Optimization of the transport mean free path and the absorption length in random lasers with non-resonant feedback." in: Optics express, Vol. 13, Issue 22, pp. 8829-36, 2009 (PubMed).

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