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Details for Product No. ABIN1105671

Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibody

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Antigen
Synonyms MCH4, ALPS2, FLICE2, xCaspase-10, alps2, caspace-10, caspase-10, flice2, mch4, xCaspace-10
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN1105671
Quantity 50 µg
Price
399.30 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide at C-terminus of human Caspase-10
Isotype IgG
Specificity This antibody recognises the 59kD apoptosis associated protein designated Caspase-10beta. The antibody only recognises the FLICE 2 form of Caspase-10.
Purification Purified
Alternative Name Caspase-10
Background Caspase-10 is a novel ICE/CED-3 protease, and cleaves and activates Caspase -3, -4, -6, -7, -8 and -9 leading to the cleavage of many key proteins such as PARP. Caspase-10 exists in two forms that differ in sequence at the C-terminus. Caspase-10 is also known as Mch4, whilst Caspase-10beta is also known as FLICE2.
Alternate names: Apoptotic protease Mch-4, CASP-10, CASP10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, MCH4
Gene ID 843
NCBI Accession NP_001193453.1
UniProt Q92851
Research Area Apoptosis/Necrosis
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline containing 0.02% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Chavrier, Vingron, Sander et al.: "Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line." in: Molecular and cellular biology, Vol. 10, Issue 12, pp. 6578-85, 1991 (PubMed).

Vincenz, Dixit: "Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling." in: The Journal of biological chemistry, Vol. 272, Issue 10, pp. 6578-83, 1997 (PubMed).

Alternatives for antigen "Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10)", type "Antibodies"
Hosts (105), (8), (3), (1)
Reactivities (117), (18), (16), (2), (2), (2)
Applications (94), (39), (26), (17), (15), (10), (10), (7), (4), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (28), (6), (5), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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