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Caspase 9 antibody (Caspase 9, Apoptosis-Related Cysteine Peptidase) (AA 41-56)

Details for Product anti-CASP9 Antibody No. ABIN1105684, Supplier: Login to see
Antigen
  • CASP9
  • AI115399
  • APAF-3
  • AW493809
  • CASP-9
  • Caspase-9
  • ICE-LAP6
  • Mch6
  • Apaf3
  • Casp-9-CTD
  • Casp9_v1
  • Ice-Lap6
  • APAF3
  • MCH6
  • PPP1R56
Alternatives
anti-Human Caspase 9 antibody for Western Blotting
Epitope
AA 41-56
33
24
22
19
19
16
14
13
13
13
11
11
11
8
8
7
7
7
6
5
5
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
407
113
108
15
13
9
6
5
3
3
2
1
1
1
Host
Rabbit
415
47
1
Clonality
Polyclonal
Conjugate
This Caspase 9 antibody is un-conjugated
11
10
7
5
4
4
4
4
4
4
4
4
3
3
3
Application
Western Blotting (WB)
384
160
119
73
68
58
46
34
12
10
8
6
2
2
Supplier
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Immunogen Synthetic peptide corresponding to amino acids 41-56 of human caspase-9.
Isotype IgG
Specificity Following activation (induced by the binding of Apaf-1), caspase-9 cleaves and activates caspase-3. This antibody recognises the 46 kDa caspase-9 in Western blots.
Purification Purified
Alternative Name Caspase-9 (CASP9 Antibody Abstract)
Background Caspase-9 (also known as ICE-LAP6, McL6 and Apaf-3) plays a central role in programmed cell death.Synonyms: APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, ICE-LAP6, ICE-like apoptotic protease 6, MCH6
Gene ID 842
NCBI Accession NP_001220
UniProt P55211
Research Area Apoptosis/Necrosis, Cancer
Pathways MAPK Signaling, RTK Signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate buffered saline containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Caspase 9 antibody (Caspase 9, Apoptosis-Related Cysteine Peptidase) (AA 41-56) (ABIN1105684) anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 41-56) antibody
Background publications Li, Nijhawan, Budihardjo et al.: "Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade." in: Cell, Vol. 91, Issue 4, pp. 479-89, 1997 (PubMed).