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Caspase 9 antibody (Caspase 9, Apoptosis-Related Cysteine Peptidase) (AA 41-56)

Details for Product anti-CASP9 Antibody No. ABIN1105684, Supplier: Log in to see
Antigen
  • CASP9
  • AI115399
  • APAF-3
  • AW493809
  • CASP-9
  • Caspase-9
  • ICE-LAP6
  • Mch6
  • Apaf3
  • Casp-9-CTD
  • Casp9_v1
  • Ice-Lap6
  • APAF3
  • MCH6
  • PPP1R56
  • caspase 9
  • caspase 9, apoptosis-related cysteine peptidase
  • caspase-9-like
  • CASP9
  • LOC100101592
  • Casp9
  • LOC100518913
Alternatives
anti-Human Caspase 9 antibody for Western Blotting
Epitope
AA 41-56
37
22
21
17
17
16
15
15
13
12
11
10
9
9
8
7
6
6
6
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
410
147
140
24
14
11
7
6
6
3
2
1
Host
Rabbit
406
44
1
Clonality
Polyclonal
Conjugate
This Caspase 9 antibody is un-conjugated
11
10
7
4
4
4
4
4
4
4
4
4
4
4
4
3
3
Application
Western Blotting (WB)
385
146
133
85
72
68
53
30
23
15
13
9
6
2
2
2
Options
Supplier
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Immunogen Synthetic peptide corresponding to amino acids 41-56 of human caspase-9.
Isotype IgG
Specificity Following activation (induced by the binding of Apaf-1), caspase-9 cleaves and activates caspase-3. This antibody recognises the 46 kDa caspase-9 in Western blots.
Purification Purified
Alternative Name Caspase-9 (CASP9 Antibody Abstract)
Background Caspase-9 (also known as ICE-LAP6, McL6 and Apaf-3) plays a central role in programmed cell death.Synonyms: APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, ICE-LAP6, ICE-like apoptotic protease 6, MCH6
Gene ID 842
NCBI Accession NP_001220
UniProt P55211
Research Area Apoptosis/Necrosis, Cancer
Pathways MAPK Signaling, RTK Signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Phosphate buffered saline containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Caspase 9 antibody (Caspase 9, Apoptosis-Related Cysteine Peptidase) (AA 41-56) (ABIN1105684) anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 41-56) antibody
Background publications Li, Nijhawan, Budihardjo, Srinivasula, Ahmad, Alnemri, Wang: "Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade." in: Cell, Vol. 91, Issue 4, pp. 479-89, 1997 (PubMed).