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Chromobox Homolog 1 (CBX1) antibody

Details for Product No. ABIN1105709, Supplier: Log in to see
Antigen
  • Cbx
  • Cbx-rs2
  • E430007M08Rik
  • HP1B
  • Hp1beta
  • M31
  • MOD1
  • CBX
  • HP1-BETA
  • HP1Hs-beta
  • HP1Hsbeta
  • p25beta
  • cbx1
  • wu:fe14b09
  • zgc:55739
Reactivity
Human, Monkey
86
29
19
8
5
4
2
1
1
1
1
1
1
1
Host
Mouse
42
25
20
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
3
3
3
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
81
52
23
13
10
9
8
5
2
2
1
1
1
1
Supplier
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Clone 5A3
Isotype IgG1
Specificity This antibody recognizes CBX1
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey.
Purification Ascites
Alternative Name CBX1 (CBX1 Antibody Abstract)
Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.Synonyms: Chromobox protein homolog 1, HP1 beta, HP1-beta, HP1Hsbeta, Heterochromatin protein 1 homolog beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta
Molecular Weight 21 kDa
Gene ID 10951
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Flow Cytometry (FACS) image for anti-Chromobox Homolog 1 (CBX1) antibody (ABIN1105709) anti-Chromobox Homolog 1 (CBX1) antibody
Western Blotting (WB) image for anti-Chromobox Homolog 1 (CBX1) antibody (ABIN1105709) anti-Chromobox Homolog 1 (CBX1) antibody (Image 2)
Immunofluorescence (IF) image for anti-Chromobox Homolog 1 (CBX1) antibody (ABIN1105709) anti-Chromobox Homolog 1 (CBX1) antibody (Image 3)
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).