CCNDBP1 antibody (Internal Region)

Catalog No. ABIN1105713

Product Details anti-CCNDBP1 Antibody

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Binding Specificity: AA 322-333, Internal Region

Reactivity: Human, Cow, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This CCNDBP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-TKASHVTPQP ED

Specificity: This antibody recognizes CCNDBP1.

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Bovine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide (C-TKASHVTPQPED) from the internal region (near C-Terminus) of Human CCNDBP1 (NP_036274.3). Genename: CCNDBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Alternative Name: CCNDBP1 (CCNDBP1 Products)

Synonyms: CCNDBP1 antibody, dip1 antibody, gcip antibody, DIP1 antibody, GCIP antibody, HHM antibody, AU022347 antibody, Maid antibody, SECC-8 antibody, SSEC-8 antibody, cyclin D1 binding protein 1 antibody, cyclin D-type binding-protein 1 antibody, CCNDBP1 antibody, ccndbp1 antibody, Ccndbp1 antibody

Background: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.Synonyms: Cyclin-D1-binding protein 1, DIP1, GCIP, Grap2 and cyclin-D-interacting protein, HHM, Human homolog of Maid, MAID

Molecular Weight: 40.3 kDa (NP_036274.3)

Gene ID: 23582

NCBI Accession: NP_036274