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CD25 antibody

IL2RA Reactivity: Human FACS, Func Host: Mouse Monoclonal B-B10 unconjugated
Catalog No. ABIN1106134
  • Target See all CD25 (IL2RA) Antibodies
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Reactivity
    • 171
    • 107
    • 35
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 129
    • 80
    • 78
    • 2
    • 1
    Mouse
    Clonality
    • 209
    • 77
    • 2
    Monoclonal
    Conjugate
    • 106
    • 31
    • 26
    • 25
    • 19
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD25 antibody is un-conjugated
    Application
    • 202
    • 85
    • 50
    • 47
    • 39
    • 33
    • 19
    • 17
    • 14
    • 14
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Ion Exchange Chromatography.
    Sterility
    0.22 μm filtered
    Immunogen
    PHA activated T cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-B10
    Isotype
    IgG1
    Top Product
    Discover our top product IL2RA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
    Preservative
    Without preservative
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Alternative Name
    CD25 / IL2RA (IL2RA Products)
    Synonyms
    CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
    Background
    IL-2R (T-cell growth factor receptor) consists of a chain of 55 kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or beta chain. IL-2RA is over-expressed on the surface of activated Tcells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages. CD25 Molecule alone appears to function as a low affinity receptor and associates wtih CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55
    Gene ID
    3559
    NCBI Accession
    NP_000408
    UniProt
    P01589
    Pathways
    JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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