Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody

Details for Product No. ABIN1106249
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f ... show more
vegfr-2, KDR, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, Vegfr-2, CD309, FLK1, VEGFR, FLK-1, flk-1, FLK/KDR, flk1, flk1b, kdrb, si:busm1-205d10.1, si:ch211-254j6.1, si:ch211-278f21.4, wu:fc31a09, fk52c05, flk, kdr, kdra, vegfr2, vegfr4, vegr2, wu:fk52c05 show less
Reactivity
Human
(506), (301), (187), (64), (61), (53), (49), (26), (4), (2), (2), (2), (2), (2), (2), (2), (1)
Host
Mouse
(462), (80), (44), (3), (2), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(35), (15), (14), (10), (9), (6), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
(407), (187), (167), (121), (94), (94), (60), (40), (39), (34), (25), (15), (10), (7), (7), (4), (3), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1106249
390.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone 4B4
Isotype IgG1
Specificity This antibody recognizes Human VEGFR-2 / KDR. Other species not tested.
Purification Ascites
Alternative Name CD309 / VEGFR-2 / Flk-1
Background KDR has also been designated as VEGFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk-1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Molecular Weight 152 kDa
Gene ID 3791
Research Area Cytokines, Receptors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (2) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (Image 2)
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (3) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) antibody (Image 3)
Background publications Takahashi, Yamaguchi, Chida et al.: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, 2001 (PubMed).

Cartron, Moreau, Oliver et al.: "Involvement of the N-terminus of Bax in its intracellular localization and function." in: FEBS letters, Vol. 512, Issue 1-3, pp. 95-100, 2002 (PubMed).

Selheim, Holmsen, Vassbotn: "Identification of functional VEGF receptors on human platelets." in: FEBS letters, Vol. 512, Issue 1-3, pp. 107-10, 2002 (PubMed).

Validation Images
Did you look for something else?
back to top