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CDC27 antibody (Cell Division Cycle 27 Homolog (S. Cerevisiae))

Details for Product anti-CDC27 Antibody No. ABIN1106637, Supplier: Log in to see
Antigen
  • CDC27
  • NV10210
  • ANAPC3
  • APC3
  • CDC27Hs
  • D0S1430E
  • D17S978E
  • HNUC
  • NUC2
  • AI452358
  • BC023187
  • cell division cycle 27 homolog (S. cerevisiae)
  • cell division cycle 27
  • CDC27
  • cdc27
  • Cdc27
Reactivity
Human
119
55
48
23
18
13
11
5
5
4
4
3
2
2
1
Host
Mouse
94
43
Clonality (Clone)
Monoclonal ()
Conjugate
This CDC27 antibody is un-conjugated
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
103
64
37
27
22
14
11
6
3
3
1
1
1
Options
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Available images

Clone 5C12
Isotype IgG1
Specificity Recognizes CDC27
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name CDC27 (CDC27 Antibody Abstract)
Background Cdc27 shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. It is a component of the Anaphase Promoting Complex (APC), which is composed of eight protein subunits and is highly conserved in eucaryotic cells. The APC catalyzes the formation of the cyclin B ubiquitin conjugate that is responsible for the ubiquitin mediated proteolysis of B type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis.Synonyms: CDC27Hs, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H-NUC
Molecular Weight 91 kDa
Gene ID 996
Research Area CD Antigens, Surface Receptors of Immune Cells, Cell Cycle, Coagulation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-CDC27 antibody (Cell Division Cycle 27 Homolog (S. Cerevisiae)) (ABIN1106637) anti-Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) antibody
Immunohistochemistry (IHC) image for anti-CDC27 antibody (Cell Division Cycle 27 Homolog (S. Cerevisiae)) (ABIN1106637) anti-Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27) antibody (Image 2)
Background publications Koloteva-Levine, Pinchasi, Pereman, Zur, Brandeis, Elroy-Stein: "The Apc5 subunit of the anaphase-promoting complex/cyclosome interacts with poly(A) binding protein and represses internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 24, Issue 9, pp. 3577-87, 2004 (PubMed).

Goto, Eddy: "Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 42128-38, 2004 (PubMed).