CHD3 antibody (Chromodomain Helicase DNA Binding Protein 3)

Details for Product anti-CHD3 Antibody No. ABIN1106677, Supplier: Log in to see
Antigen
  • CG9594
  • CHD-3
  • CHD3
  • DmCHD3
  • Dmel\\CG9594
  • chd3
  • dCHD3
  • LOC568230
  • zfh
  • mi-2a
  • mi2-alpha
  • Mi-2a
  • Mi2-ALPHA
  • ZFH
  • 2600010P09Rik
  • AF020312
  • Chd7
  • Prp7
  • Prp9-1
  • CG9594 gene product from transcript CG9594-RA
  • chromodomain helicase DNA binding protein 3
  • similar to CHD3
  • Chd3
  • CHD3
  • LOC568230
  • chd3
Reactivity
Human, Mouse (Murine)
78
39
24
5
5
2
2
2
2
2
Host
Mouse
46
37
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CHD3 antibody is un-conjugated
4
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
61
38
31
20
17
15
15
13
9
3
3
Options
Supplier
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Supplier Product No.
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Clone 2G4
Isotype IgG1
Specificity This antibody reacts to CHD3.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Ascites
Alternative Name CHD3 (CHD3 Antibody Abstract)
Background This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.Synonyms: ATP-dependent helicase CHD3, CHD-3, Chromodomain-helicase-DNA-binding protein 3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH
Molecular Weight 226 kDa
Gene ID 1107
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (ABIN1106677) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody
Flow Cytometry (FACS) image for anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (ABIN1106677) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 2)
Immunofluorescence (IF) image for anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (ABIN1106677) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 3)
Western Blotting (WB) image for anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (ABIN1106677) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 4)
Background publications Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, 2008 (PubMed).

Lee, Yoshimatsu, Maeda, Ochiai, Morimatsu, Araki, Ogino, Morikawa, Arikawa: "Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules." in: Virus research, Vol. 98, Issue 1, pp. 83-91, 2003 (PubMed).

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