Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody

Details for Product No. ABIN1106677
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Antigen
Synonyms CG9594, CHD-3, CHD3, DmCHD3, Dmel\\CG9594, chd3, dCHD3, LOC568230, zfh, mi-2a, mi2-alpha, Mi-2a, Mi2-ALPHA, ZFH, 2600010P09Rik, AF020312, Chd7, Prp7, Prp9-1
Reactivity
Human, Mouse (Murine)
(46), (20), (11), (11), (11)
Host
Mouse
(28), (20)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(31), (26), (19), (13), (11), (10), (10), (9), (3), (2), (2), (1)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1106677
390.50 $
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Clone 2G4
Isotype IgG1
Specificity This antibody reacts to CHD3.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Ascites
Alternative Name CHD3
Background This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.Synonyms: ATP-dependent helicase CHD3, CHD-3, Chromodomain-helicase-DNA-binding protein 3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha, Zinc finger helicase, hZFH
Molecular Weight 226 kDa
Gene ID 1107
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody
anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (2) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 2)
anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (3) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 3)
anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (4) anti-Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody (Image 4)
Background publications Lee, Yoshimatsu, Maeda et al.: "Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules." in: Virus research, Vol. 98, Issue 1, pp. 83-91, 2003 (PubMed).

Burd, Kinyamu, Miller et al.: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, 2008 (PubMed).

Validation Images
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