Chorionic Gonadotropin (hCG) antibody

Details for Product No. ABIN1106693, Supplier: Log in to see
Antigen
  • CGB
  • CGB7
  • CGB1
  • AW108023
  • HCG
  • chorionic gonadotropin, beta polypeptide
  • chorionic gonadotropin, beta polypeptide 7
  • chorionic gonadotropin, beta polypeptide 1
  • ubiquitin-like 3
  • chorionic gonadotropin, beta polypeptide 5
  • CGB
  • CGB7
  • CGB1
  • Ubl3
  • CGB5
Reactivity
Human
181
8
4
3
2
Host
Mouse
141
25
12
9
6
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
7
3
2
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
104
54
40
39
25
21
12
10
6
4
4
4
3
2
2
2
2
1
1
1
1
1
Options
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Immunogen Purified Human Chorionic Gonadotropin.
Clone HCG-8
Isotype IgG1
Specificity Recognizes Human Chorionic gonadotropin (beta-subunit) and does not cross reacts with other Proteins (hLH, hTSH, or hFSH).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography on Protein A
Background HCG beta (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB).It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, β-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. HCG beta is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. Beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta
Gene ID 1082
NCBI Accession NP_000728
UniProt P01233
Research Area Hormones
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % Sodium Acetate or neutral PBS.
Concentration 0.1 mg/mL (after reconstitution with 1 ml PBS)
Buffer 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (IHC) image for anti-Chorionic Gonadotropin (hCG) antibody (ABIN1106693) anti-Chorionic Gonadotropin (hCG) antibody
Background publications Zygmunt, Herr, Keller-Schoenwetter, Kunzi-Rapp, Münstedt, Rao, Lang, Preissner: "Characterization of human chorionic gonadotropin as a novel angiogenic factor." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 11, pp. 5290-6, 2002 (PubMed).

Bo, Boime: "Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo." in: The Journal of biological chemistry, Vol. 267, Issue 5, pp. 3179-84, 1992 (PubMed).

Policastro, Ovitt, Hoshina, Fukuoka, Boothby, Boime: "The beta subunit of human chorionic gonadotropin is encoded by multiple genes." in: The Journal of biological chemistry, Vol. 258, Issue 19, pp. 11492-9, 1983 (PubMed).