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CXCL10 antibody

CXCL10 Reactivity: Human WB, EIA, IHC (fro), IF Host: Mouse Monoclonal 6D4 unconjugated
Catalog No. ABIN1106851
  • Target See all CXCL10 Antibodies
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Reactivity
    • 85
    • 36
    • 25
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 87
    • 30
    • 4
    • 3
    • 2
    • 1
    Mouse
    Clonality
    • 87
    • 39
    Monoclonal
    Conjugate
    • 62
    • 28
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCL10 antibody is un-conjugated
    Application
    • 83
    • 59
    • 30
    • 24
    • 14
    • 14
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
    Specificity
    The monoclonal antibody 6D4 recognizes Human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography
    Immunogen
    Recombinant Human IP-10
    Clone
    6D4
    Isotype
    IgG2a
    Top Product
    Discover our top product CXCL10 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide, 0.1 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 2-8 °C.
  • Target
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Alternative Name
    CXCL10 / IP-10 (CXCL10 Products)
    Synonyms
    CXCL10 antibody, C7 antibody, IFI10 antibody, INP10 antibody, IP-10 antibody, SCYB10 antibody, crg-2 antibody, gIP-10 antibody, mob-1 antibody, CRG-2 antibody, IP10 antibody, Ifi10 antibody, Scyb10 antibody, C-X-C motif chemokine ligand 10 antibody, C-X-C motif chemokine 10 antibody, chemokine (C-X-C motif) ligand 10 antibody, CXCL10 antibody, cxl10 antibody, Cxcl10 antibody
    Background
    IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFN gamma inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation.Synonyms: 10 kDa interferon-gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, INP10, SCYB10, Small-inducible cytokine B10
    Gene ID
    3627
    NCBI Accession
    NP_001556
    UniProt
    P02778
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