Keratin 5 (KRT5) antibody

Details for Product No. ABIN1106931, Supplier: Log in to see
Antigen
  • ckii
  • wu:fb02h09
  • wu:fj02d02
  • wu:fk78b12
  • zfCKII
  • KRT75
  • CK5
  • DDD
  • DDD1
  • EBS2
  • K5
  • KRT5A
  • 3300001P10Rik
  • AW146334
  • Krt2-5
  • Tfip8
  • Sak57
  • CK-5
  • Keratin-5
  • keratin 71
  • keratin 5
  • KRT71
  • krt5
  • KRT5
  • Krt5
Reactivity
Human
319
95
45
43
9
9
3
3
3
2
2
1
1
Host
Mouse
218
111
5
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
13
9
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
264
191
180
111
105
48
40
13
10
9
8
4
3
2
1
1
Options
Supplier
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Clone 3E2F1
Isotype IgG1
Specificity Recognizes Cytokeratin 5
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name Cytokeratin 5 (KRT5 Antibody Abstract)
Background CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.Synonyms: 58 kDa Cytokeratin, CK5, Cytokeratin-5, K5, KRT5, Keratin 5, Keratin type II cytoskeletal 5, Keratin-5
Gene ID 3852
Research Area Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-Keratin 5 (KRT5) antibody (ABIN1106931) anti-Keratin 5 (KRT5) antibody
Immunohistochemistry (IHC) image for anti-Keratin 5 (KRT5) antibody (ABIN1106931) anti-Keratin 5 (KRT5) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Keratin 5 (KRT5) antibody (ABIN1106931) anti-Keratin 5 (KRT5) antibody (Image 3)
Background publications Canedo-Patzi, León-Bojorge, de Ortíz-Hidalgo: "[Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases]." in: Gaceta médica de México, Vol. 142, Issue 1, pp. 59-66, 2006 (PubMed).

Leibl, Moinfar: "Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation." in: The American journal of surgical pathology, Vol. 30, Issue 4, pp. 450-6, 2006 (PubMed).