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Desmoglein 3 antibody

DSG3 Reactivity: Human WB, IF, IP, IHC (p), IHC (fro) Host: Mouse Monoclonal 5G11 unconjugated
Catalog No. ABIN1106983
  • Target See all Desmoglein 3 (DSG3) Antibodies
    Desmoglein 3 (DSG3)
    Reactivity
    • 67
    • 21
    • 16
    Human
    Host
    • 61
    • 26
    Mouse
    Clonality
    • 60
    • 27
    Monoclonal
    Conjugate
    • 36
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoglein 3 antibody is un-conjugated
    Application
    • 64
    • 35
    • 20
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The monoclonal antibody 5G11 reacts with the 140 kDa desmoglein 3 protein. Furthermore it is not cross reactive with desmoglein 1 or desmoglein 2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Protein G
    Clone
    5G11
    Isotype
    IgG1
    Top Product
    Discover our top product DSG3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Storage
    4 °C/-20 °C
    Storage Comment
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Desmoglein 3 (DSG3)
    Alternative Name
    Desmoglein-3 (DSG3 Products)
    Synonyms
    DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody
    Background
    Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
    Gene ID
    1830
    NCBI Accession
    NP_001935
    UniProt
    P32926
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