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anti-Adrenocorticotropic Hormone antibody

Overview

Antigen: Adrenocorticotropic Hormone
Clonality: Monoclonal (57)
Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Reactivity: Human, Rat (Rattus)
Host: Mouse
Quantity: 0.2 mg (1.0 mg/ml) (Product variants)
Price: Product not available in this region.
Order number: ABIN110701
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Additional Information  » anti-Adrenocorticotropic Hormone antibody

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Antigen Adrenocorticotropic Hormone
Swiss-Prot P01189
Immunogen Keyhole Limpet Haemocyanin conjugated human ACTH (1-17)
Reactivity Human, Rat (Rattus)
Clonality Monoclonal
Format Purified
Isotype IgG1 »Matching secondary antibodies
Description ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.
Clone 57
Host Mouse
Specificity This antibody recognises 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally- occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. It does not recognise 17-39 ACTH (CLIP).

Application Details  » anti-Adrenocorticotropic Hormone antibody

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Application ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
» Click here to view 2 available protocols!
Application Notes Immunohistochemistry on formalin fixed, paraffin embedded sections. ELISA (sandwich and simple). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Protein A affinity chromatography
Buffer PBS, pH 7.2, containing 0.09% sodium azide
Storage Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Restrictions For Research Use only