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EGF antibody (Epidermal Growth Factor)

Details for Product anti-EGF Antibody No. ABIN1107062, Supplier: Log in to see
Antigen
  • AI790464
  • CEGF
  • HOMG4
  • URG
Alternatives
anti-Human EGF antibody for ELISA (Capture)
Reactivity
Human
311
122
75
15
13
7
4
3
2
1
Host
Mouse
281
138
29
10
7
4
Clonality (Clone)
Monoclonal ()
Conjugate
This EGF antibody is un-conjugated
48
24
22
10
8
8
6
6
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
303
273
89
67
46
41
26
23
20
17
16
14
11
8
6
5
4
2
2
2
2
1
Supplier
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Clone 4-00E-011
Isotype IgG1
Specificity This antibody reacts to EGF.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name EGF (EGF Antibody Abstract)
Background Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.Synonyms: Epidermal growth factor, HOMG4, Pro-epidermal growth factor, URG, Urogastrone
Molecular Weight 134 kDa
Gene ID 1950
Research Area Cancer, Growth Factors
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-EGF antibody (Epidermal Growth Factor) (ABIN1107062) anti-Epidermal Growth Factor (EGF) antibody
ELISA image for anti-EGF antibody (Epidermal Growth Factor) (ABIN1107062) anti-Epidermal Growth Factor (EGF) antibody (Image 2)
Background publications Yacoub, McKinstry, Hinman, Chung, Dent, Hagan: "Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling." in: Radiation research, Vol. 159, Issue 4, pp. 439-52, 2003 (PubMed).

Soubeyran, Kowanetz, Szymkiewicz, Langdon, Dikic: "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors." in: Nature, Vol. 416, Issue 6877, pp. 183-7, 2002 (PubMed).

Gout, Dhand, Panayotou, Fry, Hiles, Otsu, Waterfield: "Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 395-405, 1993 (PubMed).