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EGF antibody (Epidermal Growth Factor)

Details for Product anti-EGF Antibody No. ABIN1107062, Supplier: Log in to see
Antigen
  • HOMG4
  • URG
  • AI790464
  • CEGF
  • epidermal growth factor
  • pro-epidermal growth factor
  • EGF
  • egf
  • CpipJ_CPIJ020278
  • Egf
  • LOC100008808
Alternatives
anti-Human EGF antibody for ELISA (Capture)
Reactivity
Human
316
140
85
18
13
7
4
2
1
1
1
Host
Mouse
288
142
29
10
6
4
Clonality (Clone)
Monoclonal ()
Conjugate
This EGF antibody is un-conjugated
46
24
21
10
8
8
6
6
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
325
279
108
70
54
33
26
24
19
18
17
14
10
7
6
5
4
2
2
2
2
1
1
Options
Supplier
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Available images

Clone 4-00E-011
Isotype IgG1
Specificity This antibody reacts to EGF.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name EGF (EGF Antibody Abstract)
Background Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.Synonyms: Epidermal growth factor, HOMG4, Pro-epidermal growth factor, URG, Urogastrone
Molecular Weight 134 kDa
Gene ID 1950
Research Area Cancer, Growth Factors
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-EGF antibody (Epidermal Growth Factor) (ABIN1107062) anti-Epidermal Growth Factor (EGF) antibody
ELISA image for anti-EGF antibody (Epidermal Growth Factor) (ABIN1107062) anti-Epidermal Growth Factor (EGF) antibody (Image 2)
Background publications Yacoub, McKinstry, Hinman, Chung, Dent, Hagan: "Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling." in: Radiation research, Vol. 159, Issue 4, pp. 439-52, 2003 (PubMed).

Soubeyran, Kowanetz, Szymkiewicz, Langdon, Dikic: "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors." in: Nature, Vol. 416, Issue 6877, pp. 183-7, 2002 (PubMed).

Gout, Dhand, Panayotou, Fry, Hiles, Otsu, Waterfield: "Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 395-405, 1993 (PubMed).