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EPH Receptor B3 antibody (EPHB3)

Details for Product anti-EPHB3 Antibody No. ABIN1107111, Supplier: Login to see
Antigen
  • tck
  • MGC83457
  • EPHB3
  • ETK2
  • HEK2
  • TYRO6
  • AW456895
  • Cek10
  • Etk2
  • MDK5
  • Sek4
  • Tyro6
  • CEK10
  • EK10
  • ek3
  • ephb3
  • fc62d03
  • rtk3
  • wu:fc62d03
  • zek3
Alternatives
anti-Human EPH Receptor B3 antibody for ELISA
Reactivity
Human
100
32
23
4
4
Host
Mouse
69
37
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This EPH Receptor B3 antibody is un-conjugated
5
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
51
34
25
11
7
3
2
1
1
Supplier
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Clone 4A122D1
Isotype IgG2a
Specificity Recognizes EPH receptor B3 (EphB3).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name EPHB3 (EPHB3 Antibody Abstract)
Background Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.Synonyms: ETK2, Ephrin type-B receptor 3, HEK2, TYRO6, Tyrosine-protein kinase TYRO6, Tyrosine-protein kinase receptor HEK-2
Gene ID 2049
Pathways RTK Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-EPH Receptor B3 antibody (EPHB3) (ABIN1107111) anti-EPH Receptor B3 (EPHB3) antibody
Immunohistochemistry (IHC) image for anti-EPH Receptor B3 antibody (EPHB3) (ABIN1107111) anti-EPH Receptor B3 (EPHB3) antibody (Image 2)
Western Blotting (WB) image for anti-EPH Receptor B3 antibody (EPHB3) (ABIN1107111) anti-EPH Receptor B3 (EPHB3) antibody (Image 3)
Background publications Trivier, Ganesan: "RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 23037-43, 2002 (PubMed).

McClelland, Hochachka, Weber: "Carbohydrate utilization during exercise after high-altitude acclimation: a new perspective." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 17, pp. 10288-93, 1998 (PubMed).

Hock, Böhme, Karn et al.: "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 17, pp. 9779-84, 1998 (PubMed).

Zhou: "The Eph family receptors and ligands." in: Pharmacology & therapeutics, Vol. 77, Issue 3, pp. 151-81, 1998 (PubMed).