EPH Receptor B6 (EPHB6) antibody

Details for Product No. ABIN1107117
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Antigen
Synonyms CEK9, EPHB5, Cekl, Mep, HEP
Reactivity
Human
(95), (33), (27), (13), (12)
Host
Mouse
(71), (22), (4), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(76), (54), (39), (21), (13), (12), (10), (5), (3), (3), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1107117
390.50 $
Plus shipping costs $45.00

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone 2A6B9
Isotype IgG1
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name EPHB6
Background EhpB6: EPH receptor B6. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.Synonyms: EPH-6, Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6
Gene ID 2051
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-EPH Receptor B6 (EPHB6) antibody anti-EPH Receptor B6 (EPHB6) antibody
anti-EPH Receptor B6 (EPHB6) antibody (2) anti-EPH Receptor B6 (EPHB6) antibody (Image 2)
Background publications Freywald, Sharfe, Roifman: "The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1." in: The Journal of biological chemistry, Vol. 277, Issue 6, pp. 3823-8, 2002 (PubMed).

Luo, Yu, Wu et al.: "EphB6 crosslinking results in costimulation of T cells." in: The Journal of clinical investigation, Vol. 110, Issue 8, pp. 1141-50, 2002 (PubMed).

Freywald, Sharfe, Rashotte et al.: "The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10150-6, 2003 (PubMed).

Fox, Kandpal: "Transcriptional silencing of EphB6 receptor tyrosine kinase in invasive breast carcinoma cells and detection of methylated promoter by methylation specific PCR." in: Biochemical and biophysical research communications, Vol. 340, Issue 1, pp. 268-76, 2005 (PubMed).

Validation Images
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