Fibulin 5 antibody (FBLN5)

Details for Product anti-FBLN5 Antibody No. ABIN1107240, Supplier: Log in to see
Antigen
  • zgc:103575
  • FBLN5
  • MGC108414
  • Fibulin-5
  • DKFZp469K0327
  • ADCL2
  • ARCL1A
  • ARMD3
  • DANCE
  • EVEC
  • FIBL-5
  • UP50
  • A55
  • fibulin 5
  • Fibulin 5
  • fbln5
  • FBLN5
  • LOC100222931
  • Fbln5
  • LOC100155248
Reactivity
Human
123
45
36
4
3
1
1
1
1
1
Host
Mouse
83
38
16
Clonality (Clone)
Monoclonal ()
Conjugate
This Fibulin 5 antibody is un-conjugated
9
8
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
95
41
15
13
6
4
4
2
2
1
1
Options
Supplier
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Supplier Product No.
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Clone 3F8D5
Isotype IgM
Specificity Recognizes Fibulin 5 (FBLN5).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name Fibulin-5 (FBLN5 Antibody Abstract)
Background Fibulin 5 (FBLN5), with 448-amino acid protein (about 50 kDa), is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.Synonyms: DANCE, Developmental arteries and neural crest EGF-like protein, FBLN5, FIBL-5, UP50, Urine p50 protein
Gene ID 10516
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Fibulin 5 (FBLN5) antibody (ABIN1107240) anti-Fibulin 5 (FBLN5) antibody
Background publications Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, 2005 (PubMed).

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, 2005 (PubMed).

Lee, Roy, Mogford, Schiemann, Mustoe: "Fibulin-5 promotes wound healing in vivo." in: Journal of the American College of Surgeons, Vol. 199, Issue 3, pp. 403-10, 2004 (PubMed).

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