FYN antibody (FYN Oncogene Related To SRC, FGR, YES)

Details for Product anti-FYN Antibody No. ABIN1107284, Supplier: Log in to see
Antigen
  • im:6908851
  • si:dkey-119m7.5
  • zgc:109996
  • c-fyn
  • cfyn-a
  • SLK
  • SYN
  • p59-FYN
  • PKC
  • fyn
  • zgc:86720
  • AI448320
  • AW552119
  • FYN oncogene related to SRC, FGR, YES
  • FYN oncogene related to SRC, FGR, YES b
  • c-fyn protein
  • FYN oncogene related to SRC, FGR, YES a
  • Fyn proto-oncogene
  • FYN
  • fyn
  • fynb
  • Fyn
  • fyna
Alternatives
anti-Human FYN antibody for Biochemical Assay
Reactivity
Human
248
157
56
10
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8
5
5
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4
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2
1
1
Host
Mouse
137
113
19
Clonality (Clone)
Monoclonal ()
Conjugate
This FYN antibody is un-conjugated
9
9
9
8
7
7
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
249
120
62
50
33
29
26
22
5
4
3
2
2
2
2
Options
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Available images

Clone 2A10
Isotype IgG1
Specificity This antibody reacts to FYN.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Alternative Name FYN (FYN Antibody Abstract)
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.Synonyms: Proto-oncogene tyrosine-protein kinase Fyn, Protooncogene Syn, SLK, p59-Fyn
Molecular Weight 61 kDa
Gene ID 2534
Pathways JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN1107284) anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody
Flow Cytometry (FACS) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN1107284) anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (Image 2)
Immunofluorescence (IF) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN1107284) anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (Image 3)
Western Blotting (WB) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN1107284) anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (Image 4)
ELISA image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN1107284) anti-FYN Oncogene Related To SRC, FGR, YES (FYN) antibody (Image 5)
Background publications Brignatz, Paronetto, Opi, Cappellari, Audebert, Feuillet, Bismuth, Roche, Arold, Sette, Collette: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Lu, Zhu, Cvrljevic, Huang, Sarkaria, Ahkavan, Dang, Dinca, Plaisier, Oderberg, Lee, Chen, Caldwell, Xie, Loo, Seligson, Chakravari, Lee, Weinmann, Cloughesy, Nelson, Bergers, Graeber, Furnari, James, Cavenee, Johns, Mischel: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).