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Galectin 3 antibody

LGALS3 Reactivity: Human, Mouse WB, IHC (p), IHC (fro), EIA, Func Host: Mouse Monoclonal B2C10 unconjugated
Catalog No. ABIN1107301
  • Target See all Galectin 3 (LGALS3) Antibodies
    Galectin 3 (LGALS3)
    Reactivity
    • 173
    • 79
    • 48
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 160
    • 50
    • 8
    • 2
    • 1
    Mouse
    Clonality
    • 152
    • 69
    Monoclonal
    Conjugate
    • 95
    • 28
    • 21
    • 12
    • 10
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Galectin 3 antibody is un-conjugated
    Application
    • 183
    • 90
    • 73
    • 61
    • 36
    • 28
    • 27
    • 27
    • 23
    • 20
    • 14
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Specificity
    This antibody reacts with galectin-3, a 30 kDa protein.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Protein G
    Clone
    B2C10
    Isotype
    IgG1
    Top Product
    Discover our top product LGALS3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % bovine serum albumin
    Storage
    4 °C
    Storage Comment
    Store at 2 - 8 °C.
  • Target
    Galectin 3 (LGALS3)
    Alternative Name
    Galectin-3 (LGALS3 Products)
    Synonyms
    CBP 35 antibody, Gal-3 antibody, Galectin-3 antibody, leg3 antibody, galactoside-binding antibody, galectin-3 antibody, lectin antibody, soluble antibody, CBP35 antibody, GAL3 antibody, GALBP antibody, GALIG antibody, L31 antibody, LGALS2 antibody, MAC2 antibody, MGC52947 antibody, MGC75803 antibody, LGALS3 antibody, gal-3 antibody, GBP antibody, L-34 antibody, Mac-2 antibody, gal3 antibody, galectin 3 antibody, Galectin-3 antibody, avian beta-defensin 3 antibody, lectin, galactoside-binding, soluble, 3 L homeolog antibody, lectin, galactoside-binding, soluble, 3 antibody, galectin 2 antibody, lectin, galactose binding, soluble 3 antibody, LGALS3 antibody, leg3 antibody, AvBD3 antibody, lgals3.L antibody, lgals3 antibody, LGALS2 antibody, Lgals3 antibody
    Target Type
    Chemical
    Background
    Galectin-3 is a member of the galectin family. The protein is composed of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of malignancies, such as colon, breast, ovarian and uterine carcinomas. Galectin-3 has been shown to function through both intracellular and extracellular actions. Related to its intracellular functions, galectin-3 has been identified as a component of heterogeneous nuclear ribonuclear protein (hnRNP), a factor in pre-mRNA splicing, and has been found to control cell cycle and prevent T cell apoptosis. On the other hand, this protein has also been demonstrated to function as extracellular molecule in activating various types of cells, including monocytes/macrophages, mast cells, neutrophils and lymphocytes. Galectin-3 has been shown to mediate cell-cell and cell-extracellular matrix interactions.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2
    Gene ID
    3958
    NCBI Accession
    NP_002297
    UniProt
    P17931
    Pathways
    RTK Signaling
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