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Hexokinase 1 antibody (HK1)

Details for Product anti-HK1 Antibody No. ABIN1107523, Supplier: Log in to see
Antigen
  • ARABIDOPSIS THALIANA HEXOKINASE 1
  • ATHXK1
  • BB404130
  • dea
  • F19B15.160
  • F19B15_160
  • GIN2
  • GLUCOSE INSENSITIVE 2
  • HEX
  • HEX-1
  • HEXOKIN
  • Hexokinase
  • HEXOKINASE
  • hexokinase-1
  • hexokinase 1
  • HK
  • Hk-1
  • hk1
  • HK1
  • Hk1-s
  • HK1-ta
  • HK1-tb
  • HK1-tc
  • HKD
  • HKI
  • HMSNR
  • HXK1
  • im:7148527
  • mHk1-s
  • wu:fc09d08
  • wu:fc16e02
  • wu:fc21e02
  • wu:fq14b11
  • zgc:55790
  • zgc:77618
Reactivity
Human, Mouse (Murine), Rat (Rattus)
181
60
54
5
4
4
3
2
2
1
1
1
Host
Mouse
148
72
Clonality (Clone)
Monoclonal ()
Conjugate
This Hexokinase 1 antibody is un-conjugated
21
15
11
5
4
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
181
134
66
39
37
27
7
7
7
6
2
2
2
2
Supplier
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Available images

Clone 7A7
Isotype IgG1
Specificity This antibody reacts to HK1.
Cross-Reactivity (Details) Species reactivity (tested):Human, Rat and Mouse.
Purification Ascites
Alternative Name Hexokinase-1 (HK1 Antibody Abstract)
Background The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.Synonyms: Brain form hexokinase, HK1, Hexokinase type I
Molecular Weight 102 kDa
Gene ID 3098
Research Area Enzymes, Metabolism, Kinases/Phosphatases
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Immunohistochemistry (IHC) image for anti-Hexokinase 1 antibody (HK1) (ABIN1107523) anti-Hexokinase 1 (HK1) antibody
Immunofluorescence (IF) image for anti-Hexokinase 1 antibody (HK1) (ABIN1107523) anti-Hexokinase 1 (HK1) antibody (Image 2)
Western Blotting (WB) image for anti-Hexokinase 1 antibody (HK1) (ABIN1107523) anti-Hexokinase 1 (HK1) antibody (Image 3)
Background publications Martins-de-Souza, Gattaz, Schmitt, Rewerts, Marangoni, Novello, Maccarrone, Turck, Dias-Neto: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, 2009 (PubMed).

Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." in: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, 2007 (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).