Hexokinase 1 (HK1) antibody

Details for Product No. ABIN1107523
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Antigen
Synonyms
Hexokinase, hk1, HK1, HEX, HEX-1, HK, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, BB404130, Hk-1, Hk1-s, dea, mHk1-s, HEXOKIN, im:7148527, wu:fc09d08, wu:fc16e02, wu:fc21e02, wu:fq14b11, zgc:55790, ... show more
Hexokinase, hk1, HK1, HEX, HEX-1, HK, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, BB404130, Hk-1, Hk1-s, dea, mHk1-s, HEXOKIN, im:7148527, wu:fc09d08, wu:fc16e02, wu:fc21e02, wu:fq14b11, zgc:55790, zgc:77618, hexokinase-1, ARABIDOPSIS THALIANA HEXOKINASE 1, ATHXK1, F19B15.160, F19B15_160, GIN2, GLUCOSE INSENSITIVE 2, HEXOKINASE, hexokinase 1 show less
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(125), (54), (50), (12), (3), (3), (1), (1), (1), (1), (1)
Host
Mouse
(97), (54)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(13), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(135), (86), (43), (34), (22), (21), (11), (10), (9), (9), (7), (5), (3), (3), (3), (3), (1), (1)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN1107523
390.50 $
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Clone 7A7
Isotype IgG1
Specificity This antibody reacts to HK1.
Cross-Reactivity (Details) Species reactivity (tested):Human, Rat and Mouse.
Purification Ascites
Alternative Name Hexokinase-1
Background The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.Synonyms: Brain form hexokinase, HK1, Hexokinase type I
Molecular Weight 102 kDa
Gene ID 3098
Research Area Enzymes, Metabolism, Kinases/Phosphatases
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
anti-Hexokinase 1 (HK1) antibody anti-Hexokinase 1 (HK1) antibody
anti-Hexokinase 1 (HK1) antibody (2) anti-Hexokinase 1 (HK1) antibody (Image 2)
anti-Hexokinase 1 (HK1) antibody (3) anti-Hexokinase 1 (HK1) antibody (Image 3)
Background publications Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." in: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, 2007 (PubMed).

Martins-de-Souza, Gattaz, Schmitt et al.: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, 2009 (PubMed).

Validation Images
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