Interferon gamma (IFNG) antibody

Details for Product No. ABIN1107642
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Antigen
Synonyms IFNG2, IFN-g, Ifg, IFN-G, IFN-gamma, IFNG, IFG, IFI
Reactivity
Human
(355), (195), (85), (29), (20), (15), (10), (9), (7), (5), (5), (5), (4), (4), (3), (3), (1), (1)
Host
Mouse
(296), (208), (125), (19), (10), (5), (4), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(82), (55), (22), (16), (13), (12), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(395), (333), (198), (74), (59), (59), (57), (50), (44), (37), (30), (29), (19), (10), (9), (8), (7), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 0.2 mg
Shipping to United States (Change)
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Catalog No. ABIN1107642
621.50 $
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Immunogen Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)
Clone 3F1E3
Isotype IgG1
Specificity This antibody recognizes Recombinant IFNG / Interferon gamma Western Blot and ELISA. Other species not tested.
Purification Affinity Chromatography on Protein A
Alternative Name IFNG / Interferon gamma
Background Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
Alternate names: IFN-gamma, gamma IFN
Gene ID 3458
NCBI Accession NP_000610
UniProt P01579
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Interferon gamma (IFNG) antibody anti-Interferon gamma (IFNG) antibody
Background publications Tsubota, Fukagawa, Fujihara et al.: "Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, 1999 (PubMed).

Takayanagi, Ogasawara, Hida et al.: "T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma." in: Nature, Vol. 408, Issue 6812, pp. 600-5, 2000 (PubMed).

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