You are viewing an incomplete version of our website. Please click to reload the website as full version.

KLHL1 antibody (Kelch-Like 1 (Drosophila))

Details for Product anti-KLHL1 Antibody No. ABIN1107952, Supplier: Log in to see
Antigen
  • mKIAA1490
  • MRP2
  • kelch-like 1 (Drosophila)
  • kelch-like 1
  • kelch-like family member 1
  • KLHL1
  • Klhl1
Reactivity
Human
72
23
23
6
5
4
4
4
4
3
3
3
2
2
2
1
Host
Mouse
57
15
Clonality (Clone)
Monoclonal ()
Conjugate
This KLHL1 antibody is un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
67
41
12
7
6
4
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Clone 3A8
Isotype IgG1
Specificity Recognizes Kelch-like 1 protein (KLHL1)
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Background The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.Synonyms: KIAA1490, KLHL1
Molecular Weight 82 kDa
Gene ID 57626
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Supplier Images
Western Blotting (WB) image for anti-KLHL1 antibody (Kelch-Like 1 (Drosophila)) (ABIN1107952) anti-Kelch-Like 1 (Drosophila) (KLHL1) antibody
Immunofluorescence (IF) image for anti-KLHL1 antibody (Kelch-Like 1 (Drosophila)) (ABIN1107952) anti-Kelch-Like 1 (Drosophila) (KLHL1) antibody (Image 2)
Background publications Barrios-Rodiles, Brown, Ozdamar, Bose, Liu, Donovan, Shinjo, Liu, Dembowy, Taylor, Luga, Przulj, Robinson, Suzuki, Hayashizaki, Jurisica, Wrana: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).