LRG1 antibody

Catalog No. ABIN1108060

Product Details anti-LRG1 Antibody

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRG1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: The monoclonal antibody recognizes leucine-rich alpha-2-glycoprotein (LRG), a member of the leucine-rich repeat family. It can be used for immuno purification of human LRG.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein G

Immunogen: Human LRG, covalently coupled to hemocyanin using glutaraldehyde

Clone: 2F5-A2

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Alternative Name: LRG1 (LRG1 Products)

Synonyms: lrg antibody, HMFT1766 antibody, LRG antibody, 1300008B03Rik antibody, 2310031E04Rik antibody, Lrg antibody, Lrhg antibody, si:dkey-90m5.4 antibody, leucine rich alpha-2-glycoprotein 1 antibody, leucine-rich alpha-2-glycoprotein 1 L homeolog antibody, leucine-rich alpha-2-glycoprotein 1 antibody, perilipin-5 antibody, si:dkey-90m5.4 antibody, LRG1 antibody, lrg1.L antibody, Lrg1 antibody, PLIN5 antibody

Background: LRG is a plasma protein of approximately 50 kDa. LRG consists of 312 amino acids. It has 1 galactosamine and 4 glucosamine oliogosacharides attached and has 2 intrachain disulfide bonds. Leucine comprises 66 of the 312 amino acids, and LRG contains at least eight 24-amino acid leucine-rich repeats. The consensus of these residues, termed leucine-rich repeats (LRR), has been identified as an LRR-containing domain. The primary function of LRRs is to provide versatile structural framework of the formation of protein-protein interactions. LRG is expressed during granulocyte differentiation. Although several family members of the leucine-rich repeat family have been shown to be involved in signal transduction, protein-protein interaction, or cell adhesion and development, a function for LRG remains elusive. LRG has been reported as a biomarker for certain diseases including microbial infections and cancer. LRG can be detected in human neutrophils and progenitor cells, but not in peripheral blood mononuclear cells.Synonyms: LRG, Leucine-rich alpha-2-glycoprotein

Gene ID: 116844

NCBI Accession: NP_443204

UniProt: P02750

Pathways: Brown Fat Cell Differentiation