LSM2 antibody (N-Term)

Catalog No. ABIN1108066

Product Details anti-LSM2 Antibody

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Binding Specificity: AA 1-95, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LSM2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human LSm2 (1-95aa) purified from E. coli

Clone: AT2B2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LSM2

Target: LSM2 (LSM2 Homolog, U6 Small Nuclear RNA Associated (LSM2))

Alternative Name: LSM2 (LSM2 Products)

Synonyms: LSM2 antibody, 61.t00040 antibody, 18.m06211 antibody, 18.m06235 antibody, lsm2 antibody, C6orf28 antibody, G7B antibody, YBL026W antibody, snRNP antibody, D17H6S56E-2 antibody, D17H6S56E2 antibody, Dmapl antibody, Dmpkap antibody, G7b antibody, Sm-X5 antibody, SmX5 antibody, wu:fe48h10 antibody, zgc:101795 antibody, LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated antibody, U6 snRNA-associated sm-like protein Lsm2, putative antibody, u6 snRNA-associated sm-like protein lsm2 antibody, U6 snRNA-associated Sm-like protein LSm2 antibody, U6 snRNA-associated Sm-like protein LSm2, putative antibody, u6 snRNA-associated sm-like protein Lsm2 antibody, U6 snRNA-associated sm-like protein Lsm2,putative antibody, u6 snRNA-associated sm-like protein lsm2, putative antibody, LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog antibody, smx5 antibody, LSM2 antibody, PFE1020w antibody, CNC01770 antibody, EHI_068580 antibody, PCHAS_123570 antibody, BBOV_II002620 antibody, BBOV_II002860 antibody, EBI_26471 antibody, Bm1_23515 antibody, PKH_101210 antibody, CGB_C2600W antibody, lsm2 antibody, lsm2.S antibody, Lsm2 antibody, smx5 antibody

Background: LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.Synonyms: C6orf28, G7B, Small nuclear ribonuclear protein D homolog, U6 snRNA-associated Sm-like protein LSm2, snRNP core Sm-like protein Sm-x5

Gene ID: 57819

NCBI Accession: NP_067000

UniProt: Q9Y333

Pathways: Ribonucleoprotein Complex Subunit Organization