JNK2 antibody (Internal Region)

Catalog No. ABIN1108137

Product Details anti-JNK2 Antibody

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Binding Specificity: AA 217-230, Internal Region

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This JNK2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is expected to recognize isoforms beta 1 and beta 2 of JNK2 (NP_620708.1, NP_620709.1).

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine (Dog), Porcine.
Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence C-EMVLHKVLFPGRDY, from the internal region of the protein sequence according to NP_620708.1, NP_620709.1. Genename: MAPK9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for JNK2

Target: JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

Alternative Name: MAPK9 / JNK2 (MAPK9 Products)

Synonyms: MAPK9 antibody, JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, SAPK1a antibody, p54a antibody, p54aSAPK antibody, AI851083 antibody, Prkm9 antibody, JNK2-ALPHA1 antibody, MAP kinase 9 antibody, mitogen-activated protein kinase 9 antibody, MAP kinase 9 antibody, MAPK9 antibody, Mapk9 antibody, MPK9 antibody

Background: C-Jun amino terminal kinases (JNKs) are MAP kinase family members that differ from other MAP kinases in that they are phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.Synonyms: JNK-55, MAP kinase 9, Mitogen-activated protein kinase 9, PRKM9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2

Molecular Weight: 48.3 kDa (NP_620709.1).

Gene ID: 5601

NCBI Accession: NP_001128516

Pathways: MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins