MEAF6 antibody (N-Term)

Catalog No. ABIN1108194

Product Details anti-MEAF6 Antibody

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Xenopus laevis, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEAF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: HNKAAPPQIP DTRRELAELV KRKQELAETL ANLERQIYAF EGSYLEDTQM

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine, Chicken, African clawed frog, ZebrafishSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-MEAF6 antibody: synthetic peptide directed towards the N terminal of human MEAF6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for MEAF6

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Alternative Name: MEAF6 (MEAF6 Products)

Synonyms: fj63g06 antibody, wu:fj63g06 antibody, zgc:100869 antibody, C1orf149 antibody, CENP-28 antibody, EAF6 antibody, NY-SAR-91 antibody, C3H1orf149 antibody, 2310005N01Rik antibody, 2810036M01Rik antibody, RGD1310440 antibody, MYST/Esa1-associated factor 6 antibody, MYST/Esa1 associated factor 6 antibody, MYST/Esa1-associated factor 6 S homeolog antibody, meaf6 antibody, MEAF6 antibody, meaf6.S antibody, Meaf6 antibody

Background: MEAF6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.Synonyms: C1orf149, Chromatin modification-related protein MEAF6, EAF6, EAF6 homolog, Esa1-associated factor 6 homolog, MYST/Esa1-associated factor 6, NY-SAR-91, Sarcoma antigen NY-SAR-91

Gene ID: 64769

NCBI Accession: NP_073593